Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540961 | 0.87 | APEX1 (0.49) | PTGDR2ALDH1A1PTPN1 | |
| SCHEMBL6540375 | 0.86 | PTPN1 (0.45) | PTGDR2ALDH1A1PTPN1 | |
| SCHEMBL6554093 | 0.84 | PNMT (0.43) | ALDH1A1 | |
| SCHEMBL6540527 | 0.82 | TDP1 (0.51) | TDP1TSHRPTGDR2CYP2C19ALDH1A1 | |
| SCHEMBL6554091 | 0.82 | PNMT (0.39) | ALDH1A1 | |
| SCHEMBL6539185 | 0.82 | ALDH1A1 (0.68) | TSHRCYP2C19ALDH1A1ADRB3LMNA | |
| SCHEMBL6539930 | 0.81 | PTPN1 (0.45) | TDP1TSHRPTGDR2CYP2C19ALDH1A1 | |
| SCHEMBL6540974 | 0.81 | ALDH1A1 (0.52) | ALDH1A1LMNA | |
| SCHEMBL6540950 | 0.79 | ADRB3 (0.70) | CYP2C19ADRB3 | |
| SCHEMBL6540955 | 0.79 | ADRB3 (0.70) | CYP2C19ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | TDP1 1972/4885TSHR 3667/4885PTGDR2 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.