Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554091 | 0.88 | PNMT (0.39) | PNMTPKMSLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL6553063 | 0.87 | KMT2A (0.47) | POLBMAPTPKMSLC6A2KMT2A | |
| SCHEMBL6553968 | 0.86 | CYP4F2 (0.42) | POLBMAPTPKMSLC6A2KMT2A | |
| SCHEMBL6540959 | 0.84 | TDP1 (0.48) | ALDH1A1 | |
| SCHEMBL6552312 | 0.83 | HTR6 (0.48) | PNMTPOLBMAPTPKMKMT2A | |
| SCHEMBL6552730 | 0.81 | POLB (0.66) | POLBMAPTPKMSLC6A2KMT2A | |
| SCHEMBL6554516 | 0.81 | POLB (0.50) | POLBMAPTPKMKMT2ANAMPT | |
| SCHEMBL4022069 | 0.79 | POLB (0.50) | POLBMAPTPKMKMT2AALDH1A1 | |
| SCHEMBL18052468 | 0.78 | ALDH1A1 (0.53) | POLBMAPTPKMKMT2AALDH1A1 | |
| SCHEMBL6554053 | 0.78 | ADRB3 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |