Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554093 | 0.88 | PNMT (0.43) | PNMTSLC6A2SLC6A3ALDH1A1NAMPT | |
| SCHEMBL6553061 | 0.87 | KMT2A (0.38) | SLC6A2NAMPTTAAR1PKM | |
| SCHEMBL6553965 | 0.86 | NAMPT (0.37) | SLC6A2SLC6A3NAMPTTAAR1 | |
| SCHEMBL6552306 | 0.85 | HTR6 (0.47) | ALDH1A1NAMPTPKM | |
| SCHEMBL6540959 | 0.82 | TDP1 (0.48) | ALDH1A1 | |
| SCHEMBL6552726 | 0.82 | SLC6A4 (0.46) | SLC6A2SLC6A3TAAR1PKM | |
| SCHEMBL6554514 | 0.81 | MTNR1B (0.41) | SLC6A2NAMPTTAAR1PKM | |
| SCHEMBL6554050 | 0.79 | ADRB3 (0.57) | — | |
| Hydrochloric Acid SCHEMBL6553930 | 0.78 | SLC2A1 (0.57) | — | |
| SCHEMBL6553063 | 0.78 | KMT2A (0.47) | SLC6A2TAAR1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |