Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 12/20 | 0.50 |
| ▸ | CA1 | P00915 | 12/20 | 0.50 |
| ▸ | CA2 | P00918 | 12/20 | 0.50 |
| ▸ | CA4 | P22748 | 12/20 | 0.50 |
| ▸ | CA9 | Q16790 | 12/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539185 | 0.89 | ALDH1A1 (0.68) | ALDH1A1LMNA | |
| SCHEMBL6554516 | 0.83 | POLB (0.50) | LMNA | |
| SCHEMBL6540961 | 0.82 | APEX1 (0.49) | ALDH1A1 | |
| SCHEMBL6541394 | 0.82 | ABCC9 (0.44) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL6540375 | 0.81 | PTPN1 (0.45) | ALDH1A1 | |
| SCHEMBL6680807 | 0.81 | AKR1C3 (0.48) | ALDH1A1 | |
| SCHEMBL6540959 | 0.81 | TDP1 (0.48) | ALDH1A1LMNA | |
| SCHEMBL6554514 | 0.81 | MTNR1B (0.41) | — | |
| SCHEMBL14944934 | 0.79 | SLC6A4 (0.56) | ALDH1A1 | |
| SCHEMBL9651945 | 0.79 | SLC6A4 (0.56) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | ALDH1A1 188/4885CA12 4283/4885CA1 4181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.