Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11007463 | 0.80 | ALDH1A1 (0.46) | HTTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11001802 | 0.78 | ALDH1A1 (0.42) | HTTKMT2AALDH1A1MAPTLMNA | |
| SCHEMBL24896257 | 0.77 | NPC1 (0.37) | HTTKMT2AALDH1A1MAPTTAAR1 | |
| SCHEMBL1833672 | 0.76 | ALDH1A1 (0.42) | HTTMEN1KMT2AALDH1A1ADH1B | |
| SCHEMBL7574843 | 0.76 | ALDH1A1 (0.42) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL27457464 | 0.73 | ALDH1A1 (0.44) | HTTMEN1KMT2AALDH1A1ADH1B | |
| SCHEMBL28117845 | 0.73 | ALDH1A1 (0.39) | HTTMEN1KMT2AALDH1A1ADH1B | |
| SCHEMBL27397672 | 0.72 | ALDH1A1 (0.42) | HTTMEN1KMT2AALDH1A1NR3C2 | |
| SCHEMBL28188925 | 0.71 | ALDH1A1 (0.43) | HTTMEN1KMT2AALDH1A1ADH1B | |
| SCHEMBL677668 | 0.70 | LMNA (0.46) | HTTMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171009-A2 | Purification of tocopherols by extraction | HENKEL CORPORATION (a Delaware corp.) (US) | 1986-02-12 | — | — | EP | claimed |
| CN-105985302-B | One kind 2,5- furans diformamide diamine compound, preparation method and application | 中国科学院宁波材料技术与工程研究所 | 2019-06-07 | — | — | CN | disclosed |
| EP-3190110-A1 | ISOTHIAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-07-12 | — | — | EP | disclosed |
| CN-105985302-A | 2,5-furandicarboxamidediamine compound, and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2016-10-05 | — | — | CN | disclosed |
| US-6770428-B2 | Photothermographic materials containing high iodide core-shell emulsions | EASTMAN KODAK COMPANY | 2004-08-03 | — | — | US | disclosed |
| CN-1152866-C | Benzimidazoles, production thereof and use thereof medicaments | ���ָ��Ӣ��ķ�������Ϲ�˾ | 2004-06-09 | — | — | CN | disclosed |
| CN-1308614-A | Benzimidazoles, production thereof and use thereof medicaments | BOEHRINGER INGELHEIM PHAMA KG (DE) | 2001-08-15 | — | — | CN | disclosed |
| EP-0137746-A2 | Nitrogen substituted angiotensin converting enzyme inhibitors | FISONS plc (GB) | 1985-04-17 | — | — | EP | disclosed |