Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1833672 | 0.80 | ALDH1A1 (0.42) | ALDH1A1ADH1BADH1CADH1AADH7 | |
| SCHEMBL6542102 | 0.76 | HTT (0.43) | ALDH1A1ADH1BADH1CADH1AADH7 | |
| SCHEMBL10535478 | 0.70 | ALDH1A1 (0.40) | ALDH1A1NPSR1MEN1KMT2AHSP90AA1 | |
| SCHEMBL6503492 | 0.65 | ADH1B (0.48) | ALDH1A1ADH1BADH1CADH1AADH7 | |
| SCHEMBL43388 | 0.65 | ALDH1A1 (0.42) | ALDH1A1NPSR1ALOX15CYP2A6MEN1 | |
| SCHEMBL7978097 | 0.65 | ALDH1A1 (0.42) | ALDH1A1NPSR1ALOX15CYP2A6MEN1 | |
| SCHEMBL5516786 | 0.65 | ALDH1A1 (0.42) | ALDH1A1NPSR1ALOX15CYP2A6MEN1 | |
| SCHEMBL609177 | 0.65 | L3MBTL1 (0.43) | ALDH1A1NPSR1ALOX15MEN1KMT2A | |
| SCHEMBL8846720 | 0.65 | ALDH1A1 (0.37) | ALDH1A1NPSR1ALOX15CYP2A6MEN1 | |
| SCHEMBL7540829 | 0.64 | NPSR1 (0.52) | ALDH1A1NPSR1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873989-B1 | Process for the preparation of distyryl-biphenyl compounds | CIBA SC HOLDING AG (CH) | 2002-03-20 | — | — | EP | claimed |
| US-6031126-A | Process | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-02-29 | — | — | US | claimed |
| US-5952524-A | Process | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-09-14 | — | — | US | claimed |
| EP-0873989-A2 | Process for the preparation of distyryl-biphenyl compounds | Ciba SC Holding AG (CH) | 1998-10-28 | — | — | EP | claimed |
| EP-0873988-A2 | Process for the preparation of distyryl-biphenyl compounds | Ciba SC Holding AG (CH) | 1998-10-28 | — | — | EP | claimed |
| EP-0873989-B1 | Process for the preparation of distyryl-biphenyl compounds | CIBA SC HOLDING AG (CH) | 2002-03-20 | — | — | EP | disclosed |
| EP-0849244-B1 | Process for the preparation of distyryl-biphenylic compounds | CIBA SC HOLDING AG (CH) | 2001-06-20 | — | — | EP | disclosed |
| US-6031126-A | Process | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-02-29 | — | — | US | disclosed |
| US-5969204-A | Process for the production of distyryl-biphenyl compounds | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-10-19 | — | — | US | disclosed |
| US-5952524-A | Process | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-09-14 | — | — | US | disclosed |
| EP-0873988-A2 | Process for the preparation of distyryl-biphenyl compounds | Ciba SC Holding AG (CH) | 1998-10-28 | — | — | EP | disclosed |
| EP-0873989-A2 | Process for the preparation of distyryl-biphenyl compounds | Ciba SC Holding AG (CH) | 1998-10-28 | — | — | EP | disclosed |
| EP-0849244-A1 | Process for the preparation of distyryl-biphenylic compounds | Ciba SC Holding AG (CH) | 1998-06-24 | — | — | EP | disclosed |