Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574843 | 0.80 | ALDH1A1 (0.42) | ALDH1A1ADH1BADH1CADH1AADH7 | |
| SCHEMBL6542102 | 0.76 | HTT (0.43) | ALDH1A1ADH1BADH1CADH1AADH7 | |
| SCHEMBL11750520 | 0.75 | ALDH1A1 (0.45) | ALDH1A1KMT2ASMN1; SMN2HTTTAAR1 | |
| SCHEMBL29118486 | 0.71 | KMT2A (0.39) | ALDH1A1KMT2AMEN1SMN1; SMN2NPSR1 | |
| SCHEMBL10535478 | 0.70 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1SMN1; SMN2NPSR1 | |
| SCHEMBL31413696 | 0.69 | KMT2A (0.44) | ALDH1A1KMT2AMEN1SMN1; SMN2NPSR1 | |
| SCHEMBL3630932 | 0.69 | USP2 (0.42) | ALDH1A1KMT2AMEN1SMN1; SMN2NPSR1 | |
| SCHEMBL6503492 | 0.65 | ADH1B (0.48) | ALDH1A1ADH1BADH1CADH1AADH7 | |
| SCHEMBL7978097 | 0.65 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1NPSR1ALOX15 | |
| SCHEMBL11008346 | 0.65 | KMT2A (0.41) | ALDH1A1KMT2AMEN1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402595-B2 | Enzyme inhibitors with isoquinolinone structures | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-07-22 | — | — | US | claimed |
| US-11685681-B2 | Method for treatment of mixed electroplating wasterwater without cyanide and phosphorus-containing reductant | GUANGZHOU ULTRA UNION CHEMICALS LTD (CN) | 2023-06-27 | — | — | US | disclosed |
| US-20210380455-A1 | METHOD FOR TREATMENT OF MIXED ELECTROPLATING WASTERWATER WITHOUT CYANIDE AND PHOSPHORUS-CONTAINING REDUCTANT | GUANGZHOU ULTRA UNION CHEMICALS LTD (CN) | 2021-12-09 | — | — | US | disclosed |
| US-11136254-B2 | Method for integrated treatment of electroplating wasterwater | GUANGZHOU ULTRA UNION CHEMICALS LTD. (CN) | 2021-10-05 | — | — | US | disclosed |
| CN-213724925-U | Crystallization kettle for producing carbazide | 潍坊裕凯化工有限公司 | 2021-07-20 | — | — | CN | disclosed |
| CN-213644549-U | Centrifuge is used in carbazide production | 潍坊裕凯化工有限公司 | 2021-07-09 | — | — | CN | disclosed |
| US-20200048125-A1 | METHOD FOR INTEGRATED TREATMENT OF ELECTROPLATING WASTERWATER | GUANGZHOU ULTRA UNION CHEMICALS LTD (CN) | 2020-02-13 | — | — | US | disclosed |
| US-20130281435-A1 | THERAPEUTIC AGENT FOR IRRITABLE BOWEL SYNDROME | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2013-10-24 | — | — | US | disclosed |
| US-20110136788-A1 | THERAPEUTIC AGENT FOR IRRITABLE BOWEL SYNDROME | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-09 | — | — | US | disclosed |
| EP-2322222-A1 | THERAPEUTIC AGENT FOR IRRITABLE BOWEL SYNDROME | Takeda Pharmaceutical Company Limited (JP) | 2011-05-18 | — | — | EP | disclosed |
| EP-1604983-A1 | RECEPTOR ANTAGONIST | Takeda Pharmaceutical Company Limited (JP) | 2005-12-14 | — | — | EP | disclosed |
| US-20050148624-A1 | Jnk inhibitor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-07-07 | — | — | US | disclosed |
| EP-1484320-A1 | JNK INHIBITOR | Takeda Chemical Industries, Ltd. (JP) | 2004-12-08 | — | — | EP | disclosed |
| EP-0394563-B1 | Cyan dyes in dye-donor elements for thermal dye transfer | AGFA GEVAERT NV (BE) | 1994-03-09 | — | — | EP | disclosed |
| US-5114975-A | Insecticides and miticides | CIBA-GEIGY CORPORATION (US) | 1992-05-19 | — | — | US | disclosed |
| EP-0304402-B1 | ANILINOPHENYL THIOUREAS, ISOTHIOUREAS AND CARBODIIMIDES, THEIR PREPARATION AND THEIR USE IN PEST-CONTROL | CIBA-GEIGY AG (CH) | 1992-05-06 | — | — | EP | disclosed |
| US-5026730-A | Anilinophenylthioureas, compositions containing them, and the use thereof in pest control | CIBA-GEIGY CORPORATION (US) | 1991-06-25 | — | — | US | disclosed |
| US-5021393-A | Stable quinonediimine dyes | AGFA-GEVAERT, N.V. (BE) | 1991-06-04 | — | — | US | disclosed |
| EP-0394563-A1 | Cyan dyes in dye-donor elements for thermal dye transfer | AGFA-GEVAERT N.V. (BE) | 1990-10-31 | — | — | EP | disclosed |
| EP-0304402-A2 | Anilinophenyl thioureas, isothioureas and carbodiimides, their preparation and their use in pest-control | CIBA-GEIGY AG (CH) | 1989-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148624-A1 | Jnk inhibitor | MAPK3, MAPKAPK3, MAPK1 | ALDH1A1 4549/4885ADH1B 3912/4885ADH1C 1623/4885 |
| US-20110136788-A1 | THERAPEUTIC AGENT FOR IRRITABLE BOWEL SYNDROME | GPBAR1, GPR35, GRPR | ALDH1A1 2996/4885ADH1B 2729/4885ADH1C 2826/4885 |
| US-20130281435-A1 | THERAPEUTIC AGENT FOR IRRITABLE BOWEL SYNDROME | GPBAR1, GPR35, GRPR | ALDH1A1 3137/4885ADH1B 2620/4885ADH1C 2732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.