Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ARG1 | P05089 | 1/20 | 0.39 |
| ▸ | ARG2 | P78540 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | PARL | Q9H300 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27942905 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2HIF1AMAPK1ALDH1A1KMT2A | |
| SCHEMBL28808332 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2HIF1AMAPK1MGLLALDH1A1 | |
| SCHEMBL7653153 | 0.74 | ARG1 (0.62) | SMN1; SMN2HIF1AARG1ARG2MAPK1 | |
| SCHEMBL31212621 | 0.73 | MGLL (0.39) | HIF1AMAPK1MGLLPARLALDH1A1 | |
| SCHEMBL28071453 | 0.71 | KMT2A (0.31) | MGLLKMT2A | |
| SCHEMBL16089841 | 0.71 | ALDH1A1 (0.46) | SMN1; SMN2MGLLALDH1A1PKMRECQL | |
| SCHEMBL2450503 | 0.70 | KMT2A (0.57) | SMN1; SMN2MAPK1MGLLPARLALDH1A1 | |
| SCHEMBL875061 | 0.69 | CCNE1 (0.40) | MAPK1MGLLPARLALDH1A1PKM | |
| SCHEMBL9712261 | 0.69 | ALDH1A1 (0.41) | SMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL11042794 | 0.69 | CCNE1 (0.41) | SMN1; SMN2ALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206251-A4 | AMPLIFICATION OF FOLATE-MEDIATED TARGETING TO TUMOR CELLS USING NANOPARTICLES | ACCESS PHARMACEUTICALS AUSTRAL (AU) | 2004-06-30 | — | — | EP | disclosed |
| EP-1206251-A1 | AMPLIFICATION OF FOLATE-MEDIATED TARGETING TO TUMOR CELLS USING NANOPARTICLES | BIOTECH AUSTRALIA PTY. LIMITED (AU) | 2002-05-22 | — | — | EP | disclosed |
| WO-2000066090-A1 | AMPLIFICATION OF FOLATE-MEDIATED TARGETING TO TUMOR CELLS USING NANOPARTICLES | BIOTECH AUSTRALIA PTY LIMITED (AU) | 2000-11-09 | — | — | WO | disclosed |