Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 5/20 | 0.39 |
| ▸ | MMP12 | P39900 | 5/20 | 0.39 |
| ▸ | MMP8 | P22894 | 4/20 | 0.39 |
| ▸ | MMP13 | P45452 | 4/20 | 0.39 |
| ▸ | MMP14 | P50281 | 4/20 | 0.39 |
| ▸ | MMP16 | P51512 | 4/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 4/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27571221 | 0.84 | MYC (0.43) | MYCMMP2MMP12MMP8MMP13 | |
| SCHEMBL15150643 | 0.82 | MEN1 (0.49) | NAMPTMMP2MMP12MMP8MMP13 | |
| SCHEMBL574790 | 0.81 | CA2 (0.47) | CTSBCA1CA2CA5ACA9 | |
| SCHEMBL29013762 | 0.81 | MYC (0.41) | MYCMMP2MMP12MMP8MMP13 | |
| SCHEMBL6619733 | 0.81 | CTSB (0.39) | NAMPTMMP2MMP12MMP8MMP13 | |
| SCHEMBL31726638 | 0.81 | CA2 (0.47) | CTSBCA1CA2CA5ACA9 | |
| SCHEMBL29193217 | 0.80 | ALDH1A1 (0.50) | MYCMMP2MMP12MMP8MMP13 | |
| SCHEMBL29394818 | 0.79 | CTSB (0.52) | MYCCTSBKMT2ACYP1A2CA9 | |
| SCHEMBL34582 | 0.79 | CTSB (0.52) | MYCCTSBKMT2ACYP1A2CA9 | |
| SCHEMBL9254895 | 0.78 | HTR6 (0.56) | NAMPTMMP2MMP12MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027339-B1 | METHOD AND REAGENTS FOR N-ALKYLATING UREIDES | TARO PHARMA IND (IL) | 2004-01-02 | — | — | EP | claimed |
| CN-1699349-A | Method and reagents for N-alkylating ureides | TARO PHARMA IND (IL) | 2005-11-23 | — | — | CN | disclosed |
| CN-1273581-A | Process and reagent for N-alkylation of ureides | TARO PHARMA IND (IL) | 2000-11-15 | — | — | CN | disclosed |