Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.56 |
| ▸ | MMP2 | P08253 | 10/20 | 0.54 |
| ▸ | MMP12 | P39900 | 10/20 | 0.54 |
| ▸ | MMP13 | P45452 | 9/20 | 0.54 |
| ▸ | MMP14 | P50281 | 9/20 | 0.54 |
| ▸ | MMP8 | P22894 | 8/20 | 0.54 |
| ▸ | MMP16 | P51512 | 8/20 | 0.54 |
| ▸ | MMP9 | P14780 | 9/20 | 0.50 |
| ▸ | MMP1 | P03956 | 7/20 | 0.50 |
| ▸ | MMP3 | P08254 | 7/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10181290 | 0.81 | HSD11B1 (0.59) | HTR6MMP2MMP12MMP13MMP14 | |
| SCHEMBL15150643 | 0.79 | MEN1 (0.49) | HTR6MMP2MMP12MMP13MMP14 | |
| SCHEMBL8761231 | 0.79 | HTR6 (0.55) | HTR6MMP2MMP12MMP13MMP14 | |
| SCHEMBL574790 | 0.78 | CA2 (0.47) | — | |
| SCHEMBL6543334 | 0.78 | MYC (0.44) | HTR6MMP2MMP12MMP13MMP14 | |
| SCHEMBL6619733 | 0.78 | CTSB (0.39) | HTR6MMP2MMP12MMP13MMP14 | |
| SCHEMBL31726638 | 0.78 | CA2 (0.47) | — | |
| SCHEMBL27733563 | 0.76 | HSD11B1 (0.55) | HTR6MMP2MMP12MMP13MMP14 | |
| SCHEMBL10179490 | 0.76 | MMP2 (0.49) | HTR6MMP2MMP12MMP13MMP14 | |
| SCHEMBL4613268 | 0.76 | HTR6 (0.57) | HTR6MMP2MMP12MMP13MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5442061-A | Recording, photoresists, printing plates | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-15 | — | — | US | disclosed |