SCHEMBL6545309

SCHEMBL6545309

N=C(N)NCCCC(N)CO

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
CYP1A2 P05177 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALOX15 P16050 1/20 0.38
NPY4R P50391 6/20 0.32
NPY1R P25929 4/20 0.32
NPY2R P49146 2/20 0.32
NPY5R Q15761 2/20 0.32
TSHR P16473 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29404058 1.00 MEN1 (0.41) MEN1CYP1A2KMT2ASMN1; SMN2ALOX15
SCHEMBL30158908 0.98 MEN1 (0.40) MEN1CYP1A2KMT2ASMN1; SMN2ALOX15
Trifluoroacetic Acid SCHEMBL10871348 0.85 NPY4R (0.40) MEN1CYP1A2KMT2ASMN1; SMN2ALOX15
SCHEMBL20822004 0.83 MEN1 (0.41) MEN1CYP1A2KMT2ASMN1; SMN2ALOX15
SCHEMBL171399 0.82 MEN1 (0.40) MEN1CYP1A2KMT2ASMN1; SMN2ALOX15
SCHEMBL7158448 0.82 MEN1 (0.40) MEN1CYP1A2KMT2ASMN1; SMN2ALOX15
SCHEMBL11535264 0.82 MEN1 (0.40) MEN1CYP1A2KMT2ASMN1; SMN2ALOX15
SCHEMBL6545308 0.82 ALOX15 (0.44) MEN1CYP1A2KMT2ASMN1; SMN2ALOX15
SCHEMBL18822222 0.82 MEN1 (0.40) MEN1CYP1A2KMT2ASMN1; SMN2ALOX15
SCHEMBL5147807 0.80 MEN1 (0.45) MEN1CYP1A2KMT2ASMN1; SMN2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4604984-A1 INHIBITORS Zealand Pharma A/S (DK) 2025-08-27 EP claimed
WO-2024083919-A1 INHIBITORS ZEALAND PHARMA A/S (DK) 2024-04-25 WO claimed
US-20240076328-A1 KV1.3 BLOCKERS ZEALAND PHARMA A/S (DK) 2024-03-07 US claimed
US-11780893-B2 Kv1.3 blockers ZEALAND PHARMA A/S (DK) 2023-10-10 US claimed
US-20220251151-A1 KV1.3 BLOCKERS ZEALAND PHARMA A/S (DK) 2022-08-11 US claimed
EP-4604984-A1 INHIBITORS Zealand Pharma A/S (DK) 2025-08-27 EP disclosed
WO-2024083919-A1 INHIBITORS ZEALAND PHARMA A/S (DK) 2024-04-25 WO disclosed
US-20240076328-A1 KV1.3 BLOCKERS ZEALAND PHARMA A/S (DK) 2024-03-07 US disclosed
US-11780893-B2 Kv1.3 blockers ZEALAND PHARMA A/S (DK) 2023-10-10 US disclosed
US-20220251151-A1 KV1.3 BLOCKERS ZEALAND PHARMA A/S (DK) 2022-08-11 US disclosed
CN-114728039-A Kv1.3 blocking agents 西兰制药公司 2022-07-08 CN disclosed
US-11292820-B2 KV1.3 blockers ZEALAND PHARMA A/S (DK) 2022-04-05 US disclosed
US-20210380646-A1 KV1.3 BLOCKERS ZEALAND PHARMA A/S (DK) 2021-12-09 US disclosed
WO-2021053194-A1 KV1.3 BLOCKERS ZEALAND PHARMA A/S (DK) 2021-03-25 WO disclosed
US-6696500-B2 BIOACTIVE SUBSTANCE HAVING ACIDIC GROUP AND A BIODEGRADABLE POLYMER HAVING AN OPTIONALLY PROTECTED BASIC GROUP, SUCH AS A POLYLACTONE THAT HAS BEEN ESTERIFIED, AMIDATED, OR THIOESTERIFIED WITH A COMPOUND HAVING CYCLIC AMINO GROUPS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2004-02-24 US disclosed
EP-0815853-B1 Sustained-release preparation for bioactive substance having an acidic group TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2004-01-21 EP disclosed
US-20010038854-A1 Sustained-release preparation TAKEDA PHARMACEUTICAL COMPANY, LIMITED (JP) 2001-11-08 US disclosed
US-6264970-B1 BIODEGRADABLE POLYMER TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-07-24 US disclosed
EP-0815853-A2 Sustained-release preparation for bioactive substance having an acidic group TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11780893-B2 Kv1.3 blockers KCNA3, KCNK3, KCNN3 MEN1 3394/4885CYP1A2 4830/4885KMT2A 644/4885
US-20010038854-A1 Sustained-release preparation BMP2, PGF, AREG MEN1 3623/4885CYP1A2 4062/4885KMT2A 4788/4885
US-11292820-B2 KV1.3 blockers KCNA3, KCNK3, KCNN3 MEN1 3394/4885CYP1A2 4830/4885KMT2A 644/4885
US-20240076328-A1 KV1.3 BLOCKERS KCNA3, KCNK3, KCNN3 MEN1 3394/4885CYP1A2 4830/4885KMT2A 644/4885
US-20210380646-A1 KV1.3 BLOCKERS KCNA3, KCNK3, KCNN3 MEN1 3394/4885CYP1A2 4830/4885KMT2A 644/4885
US-20220251151-A1 KV1.3 BLOCKERS KCNA3, KCNK3, KCNN3 MEN1 3394/4885CYP1A2 4830/4885KMT2A 644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.