Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1746493 | 0.84 | MMP2 (0.55) | GRM5MMP2MMP9MMP12FFAR1 | |
| SCHEMBL6839761 | 0.81 | MAPK14 (0.46) | HNF4AGRM5MMP2MMP9MMP12 | |
| SCHEMBL4080048 | 0.80 | VNN1 (0.51) | GRM5LMNAHPGDSMN1; SMN2USP2 | |
| SCHEMBL4301156 | 0.80 | L3MBTL1 (0.53) | MMP2MMP9MMP12LMNAHPGD | |
| SCHEMBL8606277 | 0.80 | ATM (0.52) | LMNAHPGDSMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL9766594 | 0.80 | ATM (0.52) | LMNAHPGDSMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL4300998 | 0.79 | NPC1 (0.57) | MMP2MMP9MMP12FFAR1FFAR4 | |
| SCHEMBL7715052 | 0.78 | ATM (0.46) | GRM5MMP2MMP9MMP12FFAR1 | |
| SCHEMBL13284015 | 0.78 | LMNA (0.49) | MMP2MMP9MMP12FFAR1FFAR4 | |
| SCHEMBL6545360 | 0.78 | ATM (0.46) | GRM5MMP2MMP9MMP12FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000031163-A2 | POLY(ARYLENE ETHER) HOMOPOLYMER COMPOSITIONS AND METHODS OF MANUFACTURE THEREOF | ALLIEDSIGNAL INC. (US) | 2000-06-02 | — | — | WO | claimed |
| EP-1373382-A2 | NANOPOROUS LOW DIELECTRIC CONSTANT POLYMERS | Honeywell International Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| CN-1455789-A | Low dielectric constant metals with polymeric networks | HONEYWELL INT INC (US) | 2003-11-12 | — | — | CN | disclosed |
| WO-2002068516-A2 | NANOPOROUS LOW DIELECTRIC CONSTANT POLYMERS | HONEYWELL INTERNATIONAL INC. (US) | 2002-09-06 | — | — | WO | disclosed |
| WO-2000031163-A2 | POLY(ARYLENE ETHER) HOMOPOLYMER COMPOSITIONS AND METHODS OF MANUFACTURE THEREOF | ALLIEDSIGNAL INC. (US) | 2000-06-02 | — | — | WO | disclosed |