Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDE | P14735 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 8/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL838017 | 0.77 | HTR6 (0.64) | IDEHTR6ALKALOX5PTGS2 | |
| SCHEMBL838015 | 0.77 | HTR6 (0.64) | IDEHTR6ALKALOX5PTGS2 | |
| SCHEMBL7583708 | 0.72 | HTR6 (0.51) | IDEHTR6ALKALOX5PTGS2 | |
| SCHEMBL10365920 | 0.72 | DPP8 (0.55) | — | |
| SCHEMBL28381352 | 0.70 | ITGB3 (0.42) | KDM4E | |
| SCHEMBL27498945 | 0.70 | ITGB3 (0.42) | KDM4E | |
| SCHEMBL7588756 | 0.70 | IDE (0.47) | IDEHTR6ALKALOX5PTGS2 | |
| SCHEMBL29169604 | 0.70 | HTR6 (0.69) | HTR6ALKDRD2CYP19A1KDM4E | |
| SCHEMBL14286783 | 0.69 | ALOX5 (0.55) | HTR6ALKALOX5PTGS2CYP19A1 | |
| SCHEMBL29169606 | 0.69 | HTR6 (0.67) | IDEHTR6ALKALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377542-A1 | HIV PROTEASE INHIBITORS BASED ON AMINO ACID DERIVATIVES | Pharmacor Inc. (CA) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002064551-A1 | HIV PROTEASE INHIBITORS BASED ON AMINO ACID DERIVATIVES | PHARMACOR INC. (CA) | 2002-08-22 | — | — | WO | disclosed |