SCHEMBL6546078

SCHEMBL6546078

C=C(Cc1ccc(C)cc1C)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.43
NPC1 O15118 2/20 0.43
GRIN2B Q13224 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.40
HTT P42858 2/20 0.40
LMNA P02545 1/20 0.40
PSMB8 P28062 1/20 0.40
PSMB5 P28074 1/20 0.40
MAOA P21397 3/20 0.38
MAOB P27338 3/20 0.38
TNF P01375 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPT P10636 1/20 0.36
POLB P06746 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28804356 0.82 HPGD (0.47) MAOAMAOBMEN1KMT2AMAPT
SCHEMBL28638353 0.79 RAB9A (0.54) RAB9ANPC1GRIN2BSMN1; SMN2HTT
SCHEMBL10456035 0.76 TP53 (0.41) RAB9ANPC1PSMB8PSMB5TNF
SCHEMBL6546799 0.74 L3MBTL1 (0.47) RAB9ANPC1SMN1; SMN2LMNAMAOA
SCHEMBL6546362 0.74 MAOA (0.42) SMN1; SMN2LMNAMAOAMAOBMAPT
SCHEMBL18780401 0.74 TAAR1 (0.42) RAB9ANPC1PSMB8PSMB5MEN1
SCHEMBL6546074 0.74 ALDH1A1 (0.40) MAOAMAOBMAPT
SCHEMBL26846032 0.73 BCL2 (0.43) SMN1; SMN2MAPT
SCHEMBL1257788 0.72 SRC (0.62) RAB9ANPC1SMN1; SMN2PSMB8PSMB5
SCHEMBL9268656 0.72 RAB9A (0.41) RAB9ANPC1SMN1; SMN2HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed