SCHEMBL6546554

SCHEMBL6546554

O=S(=O)(O)c1ccc(-n2nnnc2S)cc1.[KH]

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 17/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5148940 0.98 PTGS2 (0.42) PTGS2
SCHEMBL10907367 0.97 PTGS2 (0.41) PTGS2
SCHEMBL10907370 0.82 PTGS2 (0.42) PTGS2
SCHEMBL5150765 0.82 PTGS2 (0.60) PTGS2
Potassium Ion SCHEMBL6546549 0.82 PTGS2 (0.42) PTGS2
SCHEMBL8655762 0.80 ALDH1A1 (0.41)
SCHEMBL4591741 0.80 LMNA (0.43)
SCHEMBL31457351 0.80 LMNA (0.43)
SCHEMBL278418 0.80 LMNA (0.43)
SCHEMBL29672419 0.80 LMNA (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0915371-B1 Photographic element containing water soluble bis AU(I) complexes EASTMAN KODAK CO (US) 2004-01-28 EP disclosed
EP-0915095-B1 Stable and water soluble bis AU(I) complexes and their synthesis EASTMAN KODAK CO (US) 2003-01-22 EP disclosed
US-6365746-B1 AN ORGANOMERCAPTAN LIGAND HAVING EITHER A SULFATO, SULFONATO, SULFINATO, PHOSPHATE OR CARBOXY GROUP; TO IMPROVE THE PHOTOSENSITIVITY OF PHOTOGRAPHIC SILVER HALIDE EMULSIONS TO ACTINIC RADIATION EASTMAN KODAK COMPANY 2002-04-02 US disclosed
US-6034249-A PHOTOGRAPHIC SENSITIZERS EASTMAN KODAK COMPANY (US) 2000-03-07 US disclosed
EP-0915095-A2 Stable and water soluble bis AU(I) complexes and their synthesis EASTMAN KODAK COMPANY (US) 1999-05-12 EP disclosed
EP-0915371-A1 Photographic element containing water soluble bis AU(I) complexes EASTMAN KODAK COMPANY (US) 1999-05-12 EP disclosed