Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP14 | P50281 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16789640 | 0.79 | FFAR4 (0.45) | FFAR4MMP2MMP9MMP14BCHE | |
| SCHEMBL6548140 | 0.79 | FFAR4 (0.45) | FFAR4MMP2MMP9MMP14BCHE | |
| SCHEMBL31619038 | 0.78 | MEN1 (0.45) | FFAR4MMP2MMP9MMP14BCHE | |
| SCHEMBL6547655 | 0.77 | PKM (0.55) | MMP2MMP9PTGS2MMP1 | |
| SCHEMBL7453744 | 0.76 | NR3C1 (0.40) | KIF11EPHX2NOD1MEN1KMT2A | |
| SCHEMBL31619041 | 0.75 | KCNH2 (0.43) | FFAR4MMP9BCHEACHEKIF11 | |
| SCHEMBL13542559 | 0.74 | FFAR4 (0.50) | FFAR4MMP2MMP9MMP14BCHE | |
| SCHEMBL7456295 | 0.72 | ADAM17 (0.38) | MMP2MMP9MMP1ADAM17 | |
| SCHEMBL514382 | 0.72 | FFAR4 (0.49) | FFAR4MMP2MMP9MMP14BCHE | |
| SCHEMBL514383 | 0.72 | PTGS2 (0.65) | FFAR4MMP2MMP9MMP14BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1162962-B1 | ALKYNYL ARYL SULFONES | LONZA AG (US) | 2004-12-01 | — | — | EP | claimed |
| EP-1162962-A4 | ALKYNYL ARYL SULFONES | LONZA AG (US) | 2002-10-30 | — | — | EP | claimed |
| EP-1162962-A1 | ALKYNYL ARYL SULFONES | LONZA INC. (US) | 2001-12-19 | — | — | EP | claimed |
| US-6232503-B1 | MICROBIOCIDES | LONZA INC. | 2001-05-15 | — | — | US | claimed |
| WO-2000056305-A1 | ALKYNYL ARYL SULFONES | LONZA INC. (US) | 2000-09-28 | — | — | WO | claimed |
| EP-1162962-B1 | ALKYNYL ARYL SULFONES | LONZA AG (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-1162962-A4 | ALKYNYL ARYL SULFONES | LONZA AG (US) | 2002-10-30 | — | — | EP | disclosed |
| EP-1162962-A1 | ALKYNYL ARYL SULFONES | LONZA INC. (US) | 2001-12-19 | — | — | EP | disclosed |
| US-6232503-B1 | MICROBIOCIDES | LONZA INC. | 2001-05-15 | — | — | US | disclosed |
| WO-2000056305-A1 | ALKYNYL ARYL SULFONES | LONZA INC. (US) | 2000-09-28 | — | — | WO | disclosed |