SCHEMBL6547424

SCHEMBL6547424

FC(F)(F)c1ccccc1-c1ccc(I)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.50
FFAR4 Q5NUL3 1/20 0.45
TRPA1 O75762 3/20 0.45
BACE1 P56817 1/20 0.45
TRPM8 Q7Z2W7 1/20 0.45
HSD11B1 P28845 2/20 0.43
SLC13A5 Q86YT5 1/20 0.42
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
SCN9A Q15858 2/20 0.41
CNR2 P34972 2/20 0.41
NOTUM Q6P988 1/20 0.41
PIK3R1 P27986 1/20 0.40
PIK3CA P42336 1/20 0.40
USP2 O75604 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22304414 0.89 AR (0.58) ARFFAR4TRPA1BACE1TRPM8
SCHEMBL24297565 0.87 AR (0.56) ARFFAR4TRPA1BACE1TRPM8
SCHEMBL5523215 0.83 KIF11 (0.54) ARFFAR4TRPA1BACE1TRPM8
SCHEMBL11286015 0.83 KIF11 (0.54) ARFFAR4TRPA1BACE1TRPM8
SCHEMBL29980535 0.83 KIF11 (0.54) ARFFAR4TRPA1BACE1TRPM8
SCHEMBL163729 0.82 HSD11B1 (0.55) ARFFAR4TRPA1BACE1TRPM8
SCHEMBL30679727 0.81 NR3C1 (0.52) ARFFAR4TRPA1BACE1TRPM8
Benzene SCHEMBL29143034 0.80 AR (0.50) ARFFAR4TRPA1BACE1TRPM8
Water SCHEMBL7091891 0.80 AR (0.55) ARFFAR4TRPA1BACE1TRPM8
Ammonia Solution, Strong SCHEMBL28126322 0.80 HSD11B1 (0.53) ARFFAR4TRPA1BACE1TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113943287-B Polycyclic aromatic compound and application thereof in electroluminescent device 清华大学 2023-02-03 CN disclosed
WO-2016022902-A1 DIAZEPANE DERIVATIVES AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. (US) 2016-02-11 WO disclosed
EP-1135977-B1 METHOD OF MANUFACTURING AN INTERLAYER VIA AND A LAMINATE PRECURSOR USEFUL THEREFOR HONEYWELL INT INC (US) 2004-01-28 EP disclosed
US-6368697-B1 Method of manufacturing an interlayer via and a laminate precursor useful for same HONEYWELL INTERNATIONAL INC. 2002-04-09 US disclosed
US-6255039-B1 Fabrication of high density multilayer interconnect printed circuit boards ISOLA LAMINATE SYSTEMS CORP. 2001-07-03 US disclosed
US-6168898-B1 A POSITIVE ACTING, PHOTOIMAGEABLE COMPOSITION HAVING, A PHOTOACID GENERATOR CAPABLE OF GENERATING AN ACID UPON EXPOSURE TO ACTINIC RADIATION, A STYRENE-MALEIC ANHYDRIDE COPOLYMER, AN EPXOY, AND A CURING CATALYST ISOLA LAMINATE SYSTEMS CORP. 2001-01-02 US disclosed
EP-1062545-A1 POSITIVE ACTING PHOTODIELECTRIC COMPOSITION Isola Laminate Systems Corporation (US) 2000-12-27 EP disclosed
US-6120693-A Method of manufacturing an interlayer via and a laminate precursor useful for same ALLIEDSIGNAL INC. (US) 2000-09-19 US disclosed
EP-0976307-A1 POSITIVE WORKING PHOTODEFINABLE RESIN COATED METAL FOR MASS PRODUCTION OF MICROVIAS IN MULTILAYER PRINTED WIRING BOARDS AlliedSignal Inc. (US) 2000-02-02 EP disclosed
EP-0976308-A1 FABRICATION OF HIGH DENSITY MULTILAYER INTERCONNECT PRINTED CIRCUIT BOARDS AlliedSignal Inc. (US) 2000-02-02 EP disclosed
WO-1996035143-A1 ACID BLEACHABLE DYE CONTAINING LITHOGRAPHIC PRINTING PLATE COMPOSITION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-11-07 WO disclosed
US-5552260-A PHOTOSENSITIVE COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-09-03 US disclosed
US-5395734-A Acid-sensitive acrylate polymers, iodonium photoinitiator, printing plates MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-03-07 US disclosed
EP-0600615-A2 Shoot and run printing materials MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-06-08 EP disclosed
EP-0599463-A2 High speed, dry processed printing plate construction MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-06-01 EP disclosed
US-5314785-A Photoinitiator which generates acid on exposure, polymer containing acid labile alkoxy alkyl ester pendant groups MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-05-24 US disclosed
EP-0559660-A1 PHOTOSENSITIVE MATERIALS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-09-15 EP disclosed
US-5225316-A A photoinitiator that generates acid on exposure to radiation and a polymer with an acid labile group MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-07-06 US disclosed
WO-1992009934-A1 PHOTOSENSITIVE MATERIALS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-06-11 WO disclosed
US-5102771-A Containing photoinitiator and polymer containing alkoxyalkyl ester groups MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-04-07 US disclosed