SCHEMBL6548616

SCHEMBL6548616

CCC(C)ON=C(C)c1cccc(OCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)c1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 4/20 0.32
PLAU P00749 1/20 0.32
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
MAPT P10636 1/20 0.31
F2 P00734 1/20 0.31
PLG P00747 1/20 0.31
PRSS2 P07478 1/20 0.31
C1S P09871 1/20 0.31
PRSS3 P35030 1/20 0.31
SMPD1 P17405 3/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6547981 0.92 PLAU (0.35) PRSS1PLAUKMT2AMEN1MAPT
SCHEMBL6548120 0.88 PRSS1 (0.35) PRSS1KMT2AMEN1TAAR1MAPT
SCHEMBL6547431 0.87 HIF1A (0.40) PRSS1KMT2AMEN1MAPTF2
SCHEMBL6547708 0.84 PRSS1 (0.34) PRSS1KMT2AMEN1MAPTF2
SCHEMBL7618743 0.84
SCHEMBL7615454 0.82
SCHEMBL6548722 0.81 ALDH1A1 (0.35) MAPTMAOAMAOBALDH1A1
SCHEMBL6547645 0.80 MAOB (0.46) KMT2AMEN1MAOAMAOBALDH1A1
SCHEMBL8659537 0.78 MAPK1 (0.41) KMT2AMAPTALDH1A1
SCHEMBL7623283 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 PRSS1 4480/4885PLAU 4847/4885KMT2A 2985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.