Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3383990 | 0.84 | LMNA (0.38) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL21482392 | 0.82 | LMNA (0.33) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL237620 | 0.81 | CTSS (0.32) | CTSSCTSKNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15669159 | 0.79 | CTSS (0.32) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4659778 | 0.79 | ESR2 (0.32) | LMNA | |
| SCHEMBL237868 | 0.79 | ALDH1A1 (0.36) | CTSSCTSKNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL466361 | 0.78 | NR4A2 (0.37) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL14865070 | 0.78 | HDAC3 (0.35) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15042772 | 0.77 | ALDH1A1 (0.35) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15669163 | 0.77 | CTSS (0.31) | CTSSCTSKRAB9ALMNACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004011505-A1 | PROCESS FOR THE COPOLYMERIZATION OF A-OLEFINS WITH VINYL MONOMERS | STICHTING DUTCH POLYMER INSTITUTE (NL) | 2004-02-05 | — | — | WO | disclosed |
| EP-1384729-A1 | Process for the radical coplymerisation of alpha-olefins with vinyl monomers | Dutch Polymer Institute (NL) | 2004-01-28 | — | — | EP | disclosed |