SCHEMBL6548144

SCHEMBL6548144

CC(=Cc1ccc(C)cc1C)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
LMNA P02545 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
POLB P06746 2/20 0.38
HTT P42858 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
KDM4E B2RXH2 2/20 0.38
HSP90AA1 P07900 1/20 0.38
ALOX12 P18054 1/20 0.38
NFE2L2 Q16236 1/20 0.37
NQO2 P16083 1/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
CRHBP P24387 2/20 0.37
CRHR2 Q13324 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ALDH1A1 P00352 3/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18789522 0.86 ALOX5 (0.41) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL25622621 0.81 TSHR (0.45) MAPTPOLBKDM4ECES2CES1
SCHEMBL842429 0.81 TSHR (0.45) MAPTPOLBKDM4ECES2CES1
SCHEMBL3668136 0.81 KCNMA1 (0.44) MAPTMEN1KMT2ALMNAHTT
SCHEMBL19579610 0.80 MAPT (0.41) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL14526415 0.80 ALDH1A1 (0.36) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL9550627 0.77 TDP1 (0.44) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL3640371 0.76 ERN1 (0.44) MAPTMEN1KMT2ALMNANQO2
SCHEMBL3678969 0.76 TDP1 (0.37) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL10433951 0.75 KDM1A (0.35) MAPTMEN1KMT2ALMNACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed