SCHEMBL3668136

SCHEMBL3668136

CC(=Cc1cc(C)ccc1O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNMA1 Q12791 1/20 0.44
LMNA P02545 3/20 0.44
MAPT P10636 3/20 0.44
KDM4E B2RXH2 2/20 0.44
HTT P42858 2/20 0.44
TRPA1 O75762 1/20 0.41
FTO Q9C0B1 1/20 0.40
MAOB P27338 1/20 0.40
TP53 P04637 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
CSNK2A1 P68400 1/20 0.38
ALOX15 P16050 2/20 0.37
HSD17B10 Q99714 2/20 0.37
ALDH1A1 P00352 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18789522 0.84 ALOX5 (0.41) KCNMA1LMNAMAPTKDM4ETDP1
SCHEMBL3640371 0.82 ERN1 (0.44) LMNAMAPTNPC1RAB9ACES2
SCHEMBL6548144 0.81 MAPT (0.38) LMNAMAPTKDM4EHTTTP53
SCHEMBL11203025 0.80 MAPT (0.46) LMNAMAPTKDM4ETRPA1NPC1
SCHEMBL4538257 0.79 ALDH1A1 (0.48) LMNAMAPTKDM4EHTTTRPA1
SCHEMBL29180389 0.77 MAPT (0.52) LMNAMAPTKDM4EHTTTRPA1
SCHEMBL4530036 0.75 GABRA1 (0.47) LMNAMAPTKDM4ETRPA1TP53
SCHEMBL3635692 0.74 AMY1A (0.42) HSD17B10
SCHEMBL3724309 0.74 MEN1 (0.36) LMNAMAPTTP53NPC1RAB9A
SCHEMBL16269077 0.74 DEGS1 (0.37) LMNAMAPTKDM4EHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2162518-A1 LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT CHEMTURA CORPORATION (US) 2010-03-17 EP disclosed
WO-2009009293-A1 LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT CHEMTURA CORPORATION (US) 2009-01-15 WO disclosed
US-20090011961-A1 Lubricant compositions stabilized with styrenated phenolic antioxidant CROMPTON HOLDING CORPORATION 2009-01-08 US disclosed