Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3635692 | 0.87 | AMY1A (0.42) | ERN1PTGS1PTGS2ALOX5NQO2 | |
| SCHEMBL3724309 | 0.87 | MEN1 (0.36) | ERN1PTGS1PTGS2ALOX5NQO2 | |
| SCHEMBL3668136 | 0.82 | KCNMA1 (0.44) | NPC1RAB9AMEN1LMNAMAPT | |
| SCHEMBL3634452 | 0.81 | HKDC1 (0.40) | PTGS1PTGS2ALOX5NQO2ESR1 | |
| SCHEMBL18789522 | 0.80 | ALOX5 (0.41) | PTGS1PTGS2ALOX5KDM1ANPC1 | |
| SCHEMBL3727266 | 0.77 | HKDC1 (0.37) | PTGS1PTGS2ALOX5ESR1HKDC1 | |
| SCHEMBL6548144 | 0.76 | MAPT (0.38) | PTGS1PTGS2ALOX5NQO2MEN1 | |
| SCHEMBL842429 | 0.75 | TSHR (0.45) | PTGS1PTGS2ALOX5ESR1ESR2 | |
| SCHEMBL11203025 | 0.75 | MAPT (0.46) | ESR1ESR2KDM1ABRD4CREBBP | |
| SCHEMBL25622621 | 0.75 | TSHR (0.45) | PTGS1PTGS2ALOX5ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162518-A1 | LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT | CHEMTURA CORPORATION (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2009009293-A1 | LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT | CHEMTURA CORPORATION (US) | 2009-01-15 | — | — | WO | disclosed |
| US-20090011961-A1 | Lubricant compositions stabilized with styrenated phenolic antioxidant | CROMPTON HOLDING CORPORATION | 2009-01-08 | — | — | US | disclosed |