SCHEMBL6548561

SCHEMBL6548561

CCCCCCN1C(=O)c2cccc3c(Br)ccc(c23)C1=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.70
MEN1 O00255 2/20 0.70
MAPT P10636 2/20 0.70
KMT2A Q03164 2/20 0.70
ALDH1A1 P00352 2/20 0.70
KDM4E B2RXH2 1/20 0.70
NPC1 O15118 1/20 0.70
LMNA P02545 1/20 0.70
PABPC1 P11940 1/20 0.70
CYP1B1 Q16678 13/20 0.70
RGS12 O14924 1/20 0.58
USP2 O75604 1/20 0.58
MAPK1 P28482 1/20 0.58
HTT P42858 1/20 0.58
ATM Q13315 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
TLR9 Q9NR96 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
RXFP1 Q9HBX9 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21988116 1.00 POLB (0.70) POLBMEN1MAPTKMT2AALDH1A1
SCHEMBL21988126 1.00 POLB (0.70) POLBMEN1MAPTKMT2AALDH1A1
SCHEMBL28412907 1.00 POLB (0.70) POLBMEN1MAPTKMT2AALDH1A1
SCHEMBL23295238 1.00 POLB (0.70) POLBMEN1MAPTKMT2AALDH1A1
SCHEMBL31146710 1.00 POLB (0.70) POLBMEN1MAPTKMT2AALDH1A1
SCHEMBL23295234 1.00 POLB (0.70) POLBMEN1MAPTKMT2AALDH1A1
SCHEMBL30096317 1.00 POLB (0.70) POLBMEN1MAPTKMT2AALDH1A1
SCHEMBL21988152 0.99 POLB (0.72) POLBMEN1MAPTKMT2AALDH1A1
SCHEMBL30499259 0.94 POLB (0.74) POLBMEN1MAPTKMT2AALDH1A1
SCHEMBL3773566 0.94 POLB (0.74) POLBMEN1MAPTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8067827-A None JP disclosed
WO-2022120206-A2 ROOM-TEMPERATURE PHOSPHORESCENCE NANOPARTICLES AND METHODS OF MAKING THE SAME THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2022-06-09 WO disclosed
CN-110183380-B Synthesis method and application of 4-hydroxy-1, 8-naphthalimide derivative 青岛大学 2020-10-23 CN disclosed
WO-2017146400-A1 COMPOUND AND COMPOSITION FOR DETECTING PHOSGENE AND DIETHYL CHLOROPHOSPHATE EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) 2017-08-31 WO disclosed
US-20170240557-A1 COMPOUND AND COMPOSITION FOR DETECTING PHOSGENE AND DIETHYL CHLOROPHOSPHATE EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) 2017-08-24 US disclosed
US-20170240557-A1 COMPOUND AND COMPOSITION FOR DETECTING PHOSGENE AND DIETHYL CHLOROPHOSPHATE EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) 2017-08-24 US disclosed
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 US disclosed
US-9246106-B2 Electron deficient molecules and their use in organic electronic applications THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2016-01-26 US disclosed
EP-2760941-A2 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY Nitto Denko Corporation (JP) 2014-08-06 EP disclosed
US-20140193923-A1 SENSORS AND METHODS FOR DETECTING PEROXIDE BASED EXPLOSIVES UNIVERSITY OF UTAH 2014-07-10 US disclosed
WO-2013049062-A2 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-04-04 WO disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 US disclosed
US-20120255615-A1 Electron Deficient Molecules and their use in Organic Electronic Applications LELAND STANFORD JUNIOR UNIVERSITY, THE BOARD OF TRUSTEES OF THE 2012-10-11 US disclosed
US-7192967-B1 Cyclic imide-substituted pyridylalkane, alkene, alkine carboxamides useful as cytostatic and immunosuppressive agents ASTELLAS PHARMA GMBH (DE) 2007-03-20 US disclosed
US-6706855-B1 CATIONIC POLY(HEXAMETHYLENEBIGUANIDE) BOUND TO CHROMOPHORIC LABEL AVECIA LIMITED (GB) 2004-03-16 US disclosed
EP-1213967-B1 ANTIMICROBIAL POLYMER AVECIA LTD (GB) 2004-02-04 EP disclosed
EP-1213967-A1 ANTIMICROBIAL POLYMER Avecia Limited (GB) 2002-06-19 EP disclosed
WO-2001017356-A1 ANTIMICROBIAL POLYMER AVECIA LIMITED (GB) 2001-03-15 WO disclosed
JP-H0867827-A NAPHTHALIMIDE COMPOUND AND ELECTROPHOTOGRAPHIC SENSITIZER CONTAINING THE SAME RICOH CO LTD 1996-03-12 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY SUN2, NES, CRY1 POLB 2669/4885MEN1 970/4885MAPT 1709/4885
US-20170240557-A1 COMPOUND AND COMPOSITION FOR DETECTING PHOSGENE AND DIETHYL CHLOROPHOSPHATE DCPS, DCTPP1, PPIP5K2 POLB 1527/4885MEN1 2097/4885MAPT 3400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.