Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.37 |
| ▸ | RXRA | P19793 | 3/20 | 0.37 |
| ▸ | RXRB | P28702 | 3/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563 | 0.91 | FFAR4 (0.39) | FFAR4S1PR1S1PR3LPAR1ALDH1A1 | |
| SCHEMBL6889 | 0.87 | FFAR1 (0.46) | FFAR4S1PR1S1PR3FFAR1LPAR1 | |
| SCHEMBL6548 | 0.83 | PTGER4 (0.47) | FFAR4PTGER4PTGER3PTGER1PTGER2 | |
| SCHEMBL6801 | 0.83 | SMN1; SMN2 (0.46) | FFAR4S1PR1S1PR3FFAR1LPAR1 | |
| SCHEMBL7242 | 0.82 | LIPG (0.44) | FFAR4S1PR1S1PR3FFAR1LPAR1 | |
| SCHEMBL7481 | 0.81 | LPAR1 (0.55) | FFAR4S1PR1S1PR3LPAR1ALDH1A1 | |
| SCHEMBL7540 | 0.80 | LPAR1 (0.43) | S1PR1S1PR3LPAR1ALDH1A1L3MBTL1 | |
| SCHEMBL7250 | 0.78 | PPARG (0.46) | S1PR1S1PR3LPAR1ALDH1A1L3MBTL1 | |
| SCHEMBL6581 | 0.77 | CHRM1 (0.40) | FFAR4S1PR1S1PR3LPAR1ALDH1A1 | |
| SCHEMBL6861 | 0.77 | LPAR1 (0.42) | FFAR4S1PR1S1PR3LPAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483252-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | Amira Pharmaceuticals, Inc. (US) | 2012-08-08 | — | — | EP | claimed |
| WO-2011041694-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-04-07 | — | — | WO | claimed |
| EP-2483252-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | Amira Pharmaceuticals, Inc. (US) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011041694-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-04-07 | — | — | WO | disclosed |