SCHEMBL65492

SCHEMBL65492

CN(C(=O)OC(C)(C)C)C1CCNC1

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 17/20 0.42
SLC6A2 P23975 15/20 0.42
KCNH2 Q12809 3/20 0.42
SLC6A3 Q01959 10/20 0.41
HSD11B1 P28845 1/20 0.40
CYP2D6 P10635 4/20 0.40
CHRM3 P20309 1/20 0.39
MCHR1 Q99705 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL181909 1.00 SLC6A4 (0.42) SLC6A4SLC6A2KCNH2SLC6A3HSD11B1
SCHEMBL1033810 1.00 SLC6A4 (0.42) SLC6A4SLC6A2KCNH2SLC6A3HSD11B1
Hydrochloric Acid SCHEMBL31485474 0.98 SLC6A4 (0.41) SLC6A4SLC6A2KCNH2SLC6A3HSD11B1
Ammonia Solution, Strong SCHEMBL19410295 0.98 SLC6A4 (0.41) SLC6A4SLC6A2KCNH2SLC6A3HSD11B1
Hydrochloric Acid SCHEMBL25408690 0.98 SLC6A4 (0.41) SLC6A4SLC6A2KCNH2SLC6A3HSD11B1
SCHEMBL2521256 0.90 HSD11B1 (0.39) SLC6A4SLC6A2KCNH2SLC6A3HSD11B1
SCHEMBL1267151 0.90 HSD11B1 (0.39) SLC6A4SLC6A2KCNH2SLC6A3HSD11B1
SCHEMBL715627 0.90 HSD11B1 (0.39) SLC6A4SLC6A2KCNH2SLC6A3HSD11B1
SCHEMBL135183 0.90 HSD11B1 (0.42) SLC6A4SLC6A2KCNH2SLC6A3HSD11B1
SCHEMBL31085626 0.89 SLC6A4 (0.39) SLC6A4SLC6A2KCNH2SLC6A3HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 837 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106905303-A The compound and its label and their preparation method and application of one class targeting FAK 北京师范大学 2017-06-30 CN claimed
CN-106630205-A Anti-scale inhibitor for treating industrial circulating water 安徽省蓝天能源环保科技有限公司 2017-05-10 CN claimed
EP-4027995-B1 HPK1 ANTAGONISTS AND USES THEREOF NIMBUS SATURN INC (US) 2026-05-27 EP disclosed
EP-4739685-A1 1,6-NAPHTHRIDINE COMPOUNDS AS SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS Janssen Pharmaceutica NV (BE) 2026-05-13 EP disclosed
WO-2026085629-A1 SUBSTITUTED HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF Université de Montréal (CA) 2026-04-30 WO disclosed
EP-4073062-B1 FUNCTIONALIZED HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) RYVU THERAPEUTICS S A (PL) 2026-04-29 EP disclosed
EP-4682148-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2026-01-21 EP disclosed
US-20260000781-A1 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF CIDARA THERAPEUTICS INC (US) 2026-01-01 US disclosed
US-12492199-B2 Pyridopyrimidines as histamine H4-receptor inhibitors FAES FARMA, S.A. (ES) 2025-12-09 US disclosed
US-20250326748-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING REMIX THERAPEUTICS INC (US) 2025-10-23 US disclosed
US-12435128-B2 Method for predicting therapeutic effect of LSD1 inhibitor based on expression of INSM1 TAIHO PHARMACEUTICAL CO., LTD. (JP) 2025-10-07 US disclosed
EP-1001933-A1 CASPASES AND APOPTOSIS SMITHKLINE BEECHAM CORPORATION (US) 2000-05-24 EP disclosed
WO-1999021840-A1 NOVEL 7-SUBSTITUTED QUINAZOLIN-2,4-DIONES USEFUL AS ANTIBACTERIAL AGENTS WARNER-LAMBERT COMPANY (US) 1999-05-06 WO disclosed
WO-1999006367-A1 CASPASES AND APOPTOSIS SMITHKLINE BEECHAM CORPORATION (US) 1999-02-11 WO disclosed
US-5726182-A TREATMENT OF BACTERIAL INFECTIONS ABBOTT LABORATORIES (US) 1998-03-10 US disclosed
US-5599816-A BACTERICIDE ABBOTT LABORATORIES (US) 1997-02-04 US disclosed
WO-1996039407-A1 QUINOLIZINONE TYPE COMPOUNDS ABBOTT LABORATORIES (US) 1996-12-12 WO disclosed
US-5580872-A ADMINISTERING IN THE TREATMENT OF BACTERIAL INFECTIONS ABBOTT LABORATORIES (US) 1996-12-03 US disclosed
EP-0723545-A1 QUINOLIZINONE TYPE COMPOUNDS ABBOTT LABORATORIES (US) 1996-07-31 EP disclosed
WO-1995010519-A1 QUINOLIZINONE TYPE COMPOUNDS ABBOTT LABORATORIES (US) 1995-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12435128-B2 Method for predicting therapeutic effect of LSD1 inhibitor based on expression of INSM1 INMT, CARM1, KDM1B SLC6A4 3095/4885SLC6A2 2619/4885KCNH2 3038/4885
US-20260000781-A1 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF FCGR2A, FCGR1A, FCGR3B SLC6A4 1334/4885SLC6A2 901/4885KCNH2 2636/4885
US-20250326748-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING RBM17, SNRPA, SNRPA1 SLC6A4 3539/4885SLC6A2 4130/4885KCNH2 4745/4885
US-12492199-B2 Pyridopyrimidines as histamine H4-receptor inhibitors HRH4, HRH2, HRH3 SLC6A4 254/4885SLC6A2 343/4885KCNH2 378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.