SCHEMBL6550221

SCHEMBL6550221

C[CH][SiH](Cc1ccccc1)OC

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.36
TP53 P04637 1/20 0.36
TSHR P16473 2/20 0.34
MAOB P27338 2/20 0.34
CALM1 P0DP23 1/20 0.33
ALDH1A1 P00352 3/20 0.32
IDO1 P14902 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
AGXT P21549 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL296249 0.82 LTA4H (0.35) LTA4HTP53TSHRMAOBCALM1
SCHEMBL3482739 0.73 TP53 (0.42) LTA4HTP53TSHRCALM1ALDH1A1
SCHEMBL49102 0.73 TP53 (0.42) LTA4HTP53TSHRCALM1ALDH1A1
SCHEMBL7058982 0.71 TP53 (0.40) LTA4HTP53TSHRCALM1ALDH1A1
SCHEMBL9505652 0.71 TP53 (0.40) LTA4HTP53TSHRCALM1ALDH1A1
SCHEMBL4195238 0.70 LTA4H (0.39) LTA4HTP53TSHRCALM1ALDH1A1
SCHEMBL10318631 0.70 LTA4H (0.39) LTA4HTP53TSHRCALM1ALDH1A1
SCHEMBL8830313 0.68 LTA4H (0.38) LTA4HTP53TSHRMAOBCALM1
SCHEMBL14841770 0.68 TAAR1 (0.45) LTA4HTP53TSHR
Dimethylamine SCHEMBL7748343 0.68 LTA4H (0.42) LTA4HTP53TSHRCALM1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685860-B Pretreatment method of silicon dioxide 固特异轮胎和橡胶公司 2024-05-14 CN claimed
CN-114685860-A Pretreatment method of silicon dioxide 固特异轮胎和橡胶公司 2022-07-01 CN claimed
CN-114621375-B Rubber with backbone and end-group functionalization 固特异轮胎和橡胶公司 2024-06-18 CN disclosed
CN-114685860-B Pretreatment method of silicon dioxide 固特异轮胎和橡胶公司 2024-05-14 CN disclosed
CN-117986694-A Precipitated silica pretreated with coupling agent and polyethylene glycol for rubber compositions 固特异轮胎和橡胶公司 2024-05-07 CN disclosed
CN-113292772-B Accelerators for vulcanization of rubbery polymers 固特异轮胎和橡胶公司 2023-07-21 CN disclosed
CN-112608581-B Pneumatic tire 固特异轮胎和橡胶公司 2023-06-20 CN disclosed
CN-113667194-B Pneumatic tire 固特异轮胎和橡胶公司 2023-05-12 CN disclosed
CN-114685860-A Pretreatment method of silicon dioxide 固特异轮胎和橡胶公司 2022-07-01 CN disclosed
CN-114621375-A Rubber with main chain and end group functionalization 固特异轮胎和橡胶公司 2022-06-14 CN disclosed
CN-114591518-A Process for preparing silica/cellulose mixtures 固特异轮胎和橡胶公司 2022-06-07 CN disclosed
CN-112300460-A Pneumatic tire 固特异轮胎和橡胶公司 2021-02-02 CN disclosed
CN-111647206-A Pneumatic tire 固特异轮胎和橡胶公司 2020-09-11 CN disclosed
CN-111499942-A Pneumatic tire 固特异轮胎和橡胶公司 2020-08-07 CN disclosed
CN-110894314-A Resin modified oil-extended rubber 固特异轮胎和橡胶公司 2020-03-20 CN disclosed
CN-110872408-A Pneumatic tire 固特异轮胎和橡胶公司 2020-03-10 CN disclosed
EP-1448400-A1 TYRE WITH LOW ROLLING RESISTANCE, TREAD BAND AND ELASTOMERIC COMPOSITION USED THEREIN PIRELLI PNEUMATICI Società per Azioni (IT) 2004-08-25 EP disclosed
EP-1385905-A1 PRODUCT IN SUBDIVIDED FORM FOR PREPARING CROSSLINKABLE ELASTOMERIC COMPOSITIONS PIRELLI PNEUMATICI S.p.A. (IT) 2004-02-04 EP disclosed
WO-2003037655-A1 TYRE WITH LOW ROLLING RESISTANCE, TREAD BAND AND ELASTOMERIC COMPOSITION USED THEREIN PIRELLI PNEUMATICI S.P.A. (IT) 2003-05-08 WO disclosed
WO-2002083783-A1 PRODUCT IN SUBDIVIDED FORM FOR PREPARING CROSSLINKABLE ELASTOMERIC COMPOSITIONS PIRELLI PNEUMATICI S.P.A. (IT) 2002-10-24 WO disclosed