SCHEMBL6551863

SCHEMBL6551863

C=Cc1ccccc1C(=O)Nc1ccccc1S(N)(=O)=O

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 16/20 0.55
CA2 P00918 16/20 0.55
CA9 Q16790 5/20 0.51
CA12 O43570 2/20 0.50
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
KDM4E B2RXH2 1/20 0.47
CA6 P23280 1/20 0.45
CA5A P35218 1/20 0.45
CA7 P43166 1/20 0.45
CA5B Q9Y2D0 1/20 0.45
PTGES2 Q9H7Z7 1/20 0.45
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7602893 0.89 L3MBTL1 (0.44) CA1CA2CA9CA12NPC1
SCHEMBL18132557 0.80 CA1 (0.62) CA1CA2CA9CA12KMT2A
SCHEMBL6224506 0.77 CA1 (0.62) CA1CA2CA9CA12NPC1
SCHEMBL964767 0.76 CA1 (0.59) CA1CA2CA9CA12CA6
SCHEMBL29733701 0.76 CA1 (0.59) CA1CA2CA9CA12CA6
SCHEMBL6226263 0.74 CA1 (0.75) CA1CA2CA9CA12CA6
SCHEMBL6118940 0.73 CA1 (0.69) CA1CA2CA9CA12CA6
SCHEMBL4301345 0.73 MAOA (0.56) RAB9AKMT2A
SCHEMBL1142906 0.73 CA2 (0.50) CA1CA2CA9CA12CA6
SCHEMBL2255814 0.72 ALDH1A1 (0.59) NPC1RAB9AKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1048457-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-12-15 EP disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed