Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 2/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 5/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 8/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828361 | 0.86 | PSEN1 (0.52) | HCRTR2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6555278 | 0.86 | PSEN1 (0.61) | HCRTR2HCRTR1PSEN1PSEN2APH1B | |
| SCHEMBL6831693 | 0.84 | ALDH1A1 (0.48) | HCRTR2HCRTR1PSEN1PSEN2APH1B | |
| SCHEMBL6553571 | 0.83 | PSEN1 (0.46) | HCRTR2HCRTR1PSEN1PSEN2APH1B | |
| SCHEMBL6553328 | 0.81 | GLA (0.41) | HCRTR2HCRTR1PSEN1PSEN2APH1B | |
| SCHEMBL6828511 | 0.80 | HCRTR2 (0.73) | HCRTR2RORCKEAP1NFE2L2KDM1A | |
| SCHEMBL6553169 | 0.77 | ESR1 (0.40) | HCRTR2HCRTR1 | |
| SCHEMBL29078842 | 0.72 | C5AR1 (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL30582418 | 0.72 | C5AR1 (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6555394 | 0.70 | PSEN1 (0.48) | HCRTR2PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174028-B1 | SULFONAMIDE DERIVATIVES | SUMITOMO CHEM TAKEDA AGRO CO (JP) | 2004-12-22 | — | — | EP | claimed |
| US-20040067853-A1 | Sulfonamide derivative-containing agricultural and horticultural composition | NAKAYAMA MASAHARU (JP) | 2004-04-08 | — | — | US | claimed |
| US-20040023938-A1 | Sulfonamide derivatives | TABUCHI TAKANORI (JP) | 2004-02-05 | — | — | US | claimed |
| US-6586617-B1 | Nontoxic microbiocides such as 4'-chloro-N-ethyl-2'-nitro-p-toluenesulfonanilide, for agricultural or horticultural, prepared by alkylation or nitration | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2003-07-01 | — | — | US | claimed |
| EP-1174028-A1 | SULFONAMIDE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-01-23 | — | — | EP | claimed |
| EP-1174028-B1 | SULFONAMIDE DERIVATIVES | SUMITOMO CHEM TAKEDA AGRO CO (JP) | 2004-12-22 | — | — | EP | disclosed |
| US-20040067853-A1 | Sulfonamide derivative-containing agricultural and horticultural composition | NAKAYAMA MASAHARU (JP) | 2004-04-08 | — | — | US | disclosed |
| US-20040023938-A1 | Sulfonamide derivatives | TABUCHI TAKANORI (JP) | 2004-02-05 | — | — | US | disclosed |
| US-6586617-B1 | Nontoxic microbiocides such as 4'-chloro-N-ethyl-2'-nitro-p-toluenesulfonanilide, for agricultural or horticultural, prepared by alkylation or nitration | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2003-07-01 | — | — | US | disclosed |
| EP-1174028-A1 | SULFONAMIDE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067853-A1 | Sulfonamide derivative-containing agricultural and horticultural composition | NAT1, NR4A1, MRM1 | HCRTR2 316/4885HCRTR1 148/4885PSEN1 2113/4885 |
| US-20040023938-A1 | Sulfonamide derivatives | FPR1, MRM1, SULT1E1 | HCRTR2 411/4885HCRTR1 263/4885PSEN1 2647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.