Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553128 | 0.77 | HCRTR2 (0.53) | HCRTR2HCRTR1 | |
| SCHEMBL6553234 | 0.70 | HSD11B1 (0.36) | POLBLMNAKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL9340848 | 0.70 | ALDH1A1 (0.52) | POLBTDP1L3MBTL1LMNAMAPT | |
| SCHEMBL6555483 | 0.70 | ALDH1A1 (0.50) | ESR1NSD2POLBAPEX1RECQL | |
| SCHEMBL6554650 | 0.70 | MAPT (0.40) | APEX1KCNJ6KCNJ5KCNJ3BRPF1 | |
| SCHEMBL6553206 | 0.69 | ALDH1A1 (0.44) | ESR1NSD2POLBAPEX1RECQL | |
| SCHEMBL6553202 | 0.68 | HSD11B1 (0.45) | ESR1POLBESR2LMNAKCNJ6 | |
| SCHEMBL6554755 | 0.68 | ALDH1A1 (0.47) | APEX1L3MBTL1LMNAPIK3CAPIK3CD | |
| SCHEMBL6554818 | 0.67 | ALDH1A1 (0.46) | APEX1L3MBTL1LMNAPIK3CAPIK3CD | |
| SCHEMBL9634441 | 0.66 | HPGD (0.41) | ESR1NSD2POLBAPEX1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174028-B1 | SULFONAMIDE DERIVATIVES | SUMITOMO CHEM TAKEDA AGRO CO (JP) | 2004-12-22 | — | — | EP | claimed |