Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.35 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.35 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553234 | 0.85 | HSD11B1 (0.36) | HSD11B1ALDH1A1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL6554755 | 0.81 | ALDH1A1 (0.47) | HSD11B1ALDH1A1LMNAGAAMEN1 | |
| SCHEMBL6554650 | 0.74 | MAPT (0.40) | HSD11B1ALDH1A1HTTKCNJ6KCNJ5 | |
| SCHEMBL6553172 | 0.68 | ALDH1A1 (0.51) | HSD11B1ALDH1A1HTTTSHRKDM4E | |
| SCHEMBL6553169 | 0.68 | ESR1 (0.40) | ALDH1A1ESR1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL6554554 | 0.68 | HSD11B1 (0.39) | HSD11B1ALDH1A1HTTGAAPKM | |
| SCHEMBL9811626 | 0.67 | ALDH1A1 (0.47) | ALDH1A1ESR1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL9340792 | 0.67 | ALDH1A1 (0.56) | ALDH1A1KCNJ6KCNJ5KCNJ3LMNA | |
| SCHEMBL2565065 | 0.67 | TSHR (0.45) | HSD11B1ALDH1A1HTTESR2LMNA | |
| SCHEMBL9180736 | 0.64 | ESR1 (0.48) | ALDH1A1ESR1KCNJ6KCNJ5KCNJ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174028-B1 | SULFONAMIDE DERIVATIVES | SUMITOMO CHEM TAKEDA AGRO CO (JP) | 2004-12-22 | — | — | EP | claimed |