Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553172 | 0.85 | ALDH1A1 (0.51) | KMT2APIK3CAPIK3CDPIK3CBALDH1A1 | |
| SCHEMBL6554554 | 0.84 | HSD11B1 (0.39) | MAPTKMT2AALDH1A1PDE2APDE5A | |
| SCHEMBL6554755 | 0.81 | ALDH1A1 (0.47) | MAPTKMT2AVCAM1PIK3CAPIK3CD | |
| SCHEMBL6553162 | 0.80 | POLB (0.47) | MAPTVCAM1ALDH1A1KDM4EHTT | |
| SCHEMBL6553220 | 0.77 | VCAM1 (0.49) | VCAM1ALDH1A1HSD11B1KDM4EHTT | |
| SCHEMBL6553202 | 0.74 | HSD11B1 (0.45) | KMT2AARALDH1A1KCNJ6KCNJ5 | |
| SCHEMBL6553234 | 0.74 | HSD11B1 (0.36) | ARPIK3CAPIK3CDPIK3CBALDH1A1 | |
| SCHEMBL6553169 | 0.70 | ESR1 (0.40) | MAPTPIK3CAPIK3CDPIK3CBALDH1A1 | |
| SCHEMBL323126 | 0.69 | VCAM1 (0.64) | MAPTKMT2AVCAM1ALDH1A1CYP3A4 | |
| SCHEMBL6554646 | 0.69 | ALDH1A1 (0.50) | KMT2APIK3CAPIK3CDPIK3CBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174028-B1 | SULFONAMIDE DERIVATIVES | SUMITOMO CHEM TAKEDA AGRO CO (JP) | 2004-12-22 | — | — | EP | claimed |