Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.47 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553172 | 0.85 | ALDH1A1 (0.51) | ALDH1A1PDE2APDE5ACYP3A4ALOX15 | |
| SCHEMBL6554818 | 0.84 | ALDH1A1 (0.46) | ALDH1A1PDE2APDE5ACYP3A4ALOX15 | |
| SCHEMBL6553234 | 0.83 | HSD11B1 (0.36) | ALDH1A1PIK3CAPIK3CDPIK3CBHSD11B1 | |
| SCHEMBL6554650 | 0.81 | MAPT (0.40) | ALDH1A1PDE2APDE5ACYP3A4ALOX15 | |
| SCHEMBL6553202 | 0.81 | HSD11B1 (0.45) | ALDH1A1HSD11B1MEN1KMT2ALMNA | |
| SCHEMBL6553125 | 0.80 | CA9 (0.45) | ALDH1A1PDE2APDE5ACYP3A4ALOX15 | |
| SCHEMBL6554554 | 0.75 | HSD11B1 (0.39) | ALDH1A1PDE2APDE5ACYP3A4ALOX15 | |
| SCHEMBL6554646 | 0.71 | ALDH1A1 (0.50) | ALDH1A1PDE2APDE5ACYP3A4ALOX15 | |
| SCHEMBL6555483 | 0.71 | ALDH1A1 (0.50) | ALDH1A1PDE2APDE5ACYP3A4ALOX15 | |
| SCHEMBL1343971 | 0.69 | VCAM1 (0.64) | ALDH1A1PDE2APDE5ACYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174028-B1 | SULFONAMIDE DERIVATIVES | SUMITOMO CHEM TAKEDA AGRO CO (JP) | 2004-12-22 | — | — | EP | claimed |