Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.39 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13858440 | 0.81 | LMNA (0.35) | ALDH1A1CYP2A6KMT2ARAB9ACYP2A13 | |
| SCHEMBL8610584 | 0.80 | SRC (0.49) | ALDH1A1KMT2ARAB9ASMN1; SMN2MAPT | |
| SCHEMBL1665873 | 0.79 | RAB9A (0.73) | ALDH1A1CYP2A6KMT2AALDH1A3RAB9A | |
| SCHEMBL6553235 | 0.77 | LMNA (0.55) | ALDH1A1KMT2ARAB9AKDM4ELMNA | |
| SCHEMBL20473356 | 0.75 | TYR (0.58) | ALDH1A1RAB9AMAPT | |
| SCHEMBL5155573 | 0.75 | RAB9A (0.43) | ALDH1A1KMT2ARAB9ALMNASMN1; SMN2 | |
| SCHEMBL9711102 | 0.74 | MAPT (0.53) | ALDH1A1KMT2ARAB9ALMNASMN1; SMN2 | |
| SCHEMBL7781426 | 0.74 | MAPT (0.46) | ALDH1A1KMT2ARAB9AKDM4ELMNA | |
| SCHEMBL4677215 | 0.74 | ALDH1A1 (0.62) | ALDH1A1KDM4ESMN1; SMN2MAPTALDH5A1 | |
| SCHEMBL10277064 | 0.74 | CYP1A1 (0.62) | KMT2ARAB9AKDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4716685-A1 | IMIDAZO[4,5-C]PYRIDINE COMPOUNDS FOR THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2026-04-01 | — | — | EP | disclosed |
| US-20260070906-A1 | IMIDAZO[4,5-C]PYRIDINE COMPOUNDS FOR THE TREATMENT OF CANCER | HOFFMANN-LA ROCHE INC. (US) | 2026-03-12 | — | — | US | disclosed |
| US-20260060985-A1 | Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof | GALECTIN SCIENCES, LLC (US) | 2026-03-05 | — | — | US | disclosed |
| US-12377102-B2 | Compounds for the prevention and treatment of medical disorders and uses thereof | GALECTIN SCIENCES, LLC (US) | 2025-08-05 | — | — | US | disclosed |
| WO-2024240726-A1 | IMIDAZO[4,5-C]PYRIDINE COMPOUNDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2024-11-28 | — | — | WO | disclosed |
| CN-111032039-B | Compounds for the prevention and treatment of medical disorders and uses thereof | 卡莱克汀科学有限责任公司 | 2024-03-26 | — | — | CN | disclosed |
| US-20230116370-A1 | Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof | GALECTIN SCIENCES, LLC | 2023-04-13 | — | — | US | disclosed |
| US-11583530-B2 | Compounds for the prevention and treatment of medical disorders and uses thereof | GALECTIN SCIENCES, LLC (US) | 2023-02-21 | — | — | US | disclosed |
| US-11583530-B2 | Compounds for the prevention and treatment of medical disorders and uses thereof | GALECTIN SCIENCES, LLC (US) | 2023-02-21 | — | — | US | disclosed |
| US-20200147088-A1 | Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof | GALECTIN SCIENCES, LLC | 2020-05-14 | — | — | US | disclosed |
| US-20200147088-A1 | Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof | GALECTIN SCIENCES, LLC | 2020-05-14 | — | — | US | disclosed |
| CN-111032039-A | Compounds for the prevention and treatment of medical disorders and uses thereof | 卡莱克汀科学有限责任公司 | 2020-04-17 | — | — | CN | disclosed |
| EP-0358880-B1 | Use of retinoids | HOFFMANN LA ROCHE (CH) | 1994-01-19 | — | — | EP | disclosed |
| EP-0358880-A2 | Use of retinoids | F. HOFFMANN-LA ROCHE AG (CH) | 1990-03-21 | — | — | EP | disclosed |
| EP-0058370-B1 | TETRAHYDRONAPHTHALENE AND INDAN COMPOUNDS, THEIR PRODUCTION AND PHARMACEUTICAL PREPARATIONS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-12-12 | — | — | EP | disclosed |
| US-4396553-A | Tetrahydronaphthalene and indane compounds useful as anti-tumor agents | HOFFMANN-LA ROCHE INC. (US) | 1983-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260060985-A1 | Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof | LGALS3, LGALS1, LGALS2 | ALDH1A1 1833/4885CYP2A6 2282/4885KMT2A 4516/4885 |
| US-20230116370-A1 | Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof | LGALS1, LGALS2, LGALS3 | ALDH1A1 1242/4885CYP2A6 1841/4885KMT2A 4754/4885 |
| US-20260070906-A1 | IMIDAZO[4,5-C]PYRIDINE COMPOUNDS FOR THE TREATMENT OF CANCER | TLR1, TLR6, TLR8 | ALDH1A1 1320/4885CYP2A6 1747/4885KMT2A 1505/4885 |
| US-20200147088-A1 | Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof | LGALS1, LGALS2, LGALS3 | ALDH1A1 1242/4885CYP2A6 1841/4885KMT2A 4754/4885 |
| US-11583530-B2 | Compounds for the prevention and treatment of medical disorders and uses thereof | LGALS1, LGALS2, LGALS3 | ALDH1A1 1242/4885CYP2A6 1841/4885KMT2A 4754/4885 |
| US-12377102-B2 | Compounds for the prevention and treatment of medical disorders and uses thereof | LGALS1, LGALS2, LGALS3 | ALDH1A1 1242/4885CYP2A6 1841/4885KMT2A 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.