Methacrylic Acid

Methacrylic Acid

SCHEMBL6553304

C=C(C)C(=O)O.CC(C)C1=NCCO1

nearest known ligand 0.35

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
NFKB1 P19838 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL152241 0.81
SCHEMBL3341025 0.79 ADRA2A (0.38) ADRA2AADRA2BADRA2CCYP3A4
Methacrylic Acid SCHEMBL6553622 0.77 KDM4E (0.30) KDM4EPOLBCYP3A4MAPTNFKB1
Methacrylic Acid SCHEMBL6552372 0.76
SCHEMBL18614770 0.74 ADRA2A (0.39) ADRA2AADRA2BADRA2CKDM4EPOLB
Methacrylic Acid SCHEMBL6553228 0.72 KCNN4 (0.39) KDM4EPOLBCYP3A4MAPTNFKB1
Methacrylic Acid SCHEMBL28174009 0.72 KDM4E (0.31) KDM4EPOLBCYP3A4MAPTNFKB1
Methacrylic Acid SCHEMBL6553326 0.72
Methacrylic Acid SCHEMBL6552361 0.70
SCHEMBL14167280 0.69 ADRA2A (0.35) ADRA2AADRA2BADRA2CKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0978391-B1 Coating agent for ink jet recording materials and ink jet recording material ESPRIT CHEMICAL CO (US) 2004-02-11 EP disclosed
US-6548182-B1 Water-soluble polymer with 30.1-95 wt% of carboxyl groups and a crosslinking agent ESPRIT CHEMICAL CO. 2003-04-15 US disclosed
EP-0978391-A1 Coating agent for ink jet recording materials and ink jet recording material Esprit Chemical Co. (US) 2000-02-09 EP disclosed