Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GALK1 | P51570 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6554868 | 0.85 | ALDH1A1 (0.33) | KDM4EALDH1A1MAPTHPGDKDM1A | |
| Hydrochloric Acid SCHEMBL7807228 | 0.75 | ALDH1A1 (0.35) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL7644367 | 0.74 | KDM1A (0.33) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL6554859 | 0.74 | HTR7 (0.33) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL7646636 | 0.74 | SLC6A4 (0.35) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL29612346 | 0.74 | ALDH1A1 (0.37) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL1029195 | 0.73 | KDM4E (0.39) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL5859267 | 0.73 | KDM4E (0.36) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL27504827 | 0.73 | ALDH1A1 (0.36) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL7036431 | 0.72 | MAPT (0.37) | KDM4EALDH1A1MAPTHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773237-B1 | Olefin polymerization catalyst system | MITSUI CHEMICALS INC (JP) | 2004-02-18 | — | — | EP | disclosed |