Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6553477 | 0.85 | KDM4E (0.31) | ALDH1A1HSD17B10HPGDKDM4EMAPT | |
| SCHEMBL5702772 | 0.76 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CYP2A6HPGDCYP1A2 | |
| Hydrochloric Acid SCHEMBL6554723 | 0.72 | HTR2C (0.33) | ALDH1A1HSD17B10HPGDKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL4067077 | 0.71 | ALDH1A1 (0.39) | ALDH1A1HSD17B10CYP2A6HPGDCYP1A2 | |
| Hydrochloric Acid SCHEMBL4084423 | 0.71 | ALDH1A1 (0.39) | ALDH1A1HSD17B10CYP2A6HPGDCYP1A2 | |
| Hydrochloric Acid SCHEMBL4083401 | 0.71 | ALDH1A1 (0.39) | ALDH1A1HSD17B10CYP2A6HPGDCYP1A2 | |
| Hydrochloric Acid SCHEMBL6553946 | 0.71 | KDM4E (0.38) | ALDH1A1HSD17B10CYP2A6HPGDCYP1A2 | |
| Hydrochloric Acid SCHEMBL6553924 | 0.71 | KDM4E (0.33) | ALDH1A1HSD17B10CYP2A6HPGDCYP1A2 | |
| Hydrochloric Acid SCHEMBL6554982 | 0.71 | KDM4E (0.38) | ALDH1A1HSD17B10CYP2A6HPGDCYP1A2 | |
| Hydrochloric Acid SCHEMBL965025 | 0.71 | KDM4E (0.33) | ALDH1A1HSD17B10CYP2A6HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773237-B1 | Olefin polymerization catalyst system | MITSUI CHEMICALS INC (JP) | 2004-02-18 | — | — | EP | disclosed |