SCHEMBL65535

SCHEMBL65535

CC(=O)C(CCO)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.36
AKR1A1 P14550 1/20 0.36
CHRM3 P20309 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
ADRA1A P35348 1/20 0.36
HRH1 P35367 1/20 0.36
DRD3 P35462 1/20 0.36
SLC6A3 Q01959 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GABRP O00591 2/20 0.33
GABRD O14764 2/20 0.33
GABRA1 P14867 2/20 0.33
GABRB1 P18505 2/20 0.33
GABRG2 P18507 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7581969 0.88 ALDH1A1 (0.33) TDP1ALDH1A1GAASMN1; SMN2GABRP
SCHEMBL28221532 0.86 ALDH1A1 (0.32) ALDH1A1GAASMN1; SMN2
SCHEMBL9392724 0.85 CHRM1 (0.41) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL6374585 0.82 ENPEP (0.42) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL12851375 0.80 GPR84 (0.41) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL23803658 0.79 LMNA (0.33) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL223020 0.78 CHRM1 (0.55) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL6922740 0.78 GPR84 (0.44) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL11587400 0.78 CHRM1 (0.55) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL27800393 0.77 ALDH1A1 (0.32) CHRM1AKR1A1CHRM3HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118909905-A Construction method and application of optimized L-isoleucine production strain 元素驱动(杭州)生物科技有限公司 2024-11-08 CN claimed
CN-118685334-A Engineering bacterium for producing L-isoleucine and construction method and application thereof 中国科学院微生物研究所 2024-09-24 CN claimed
CN-117757651-B Method for improving L-isoleucine yield by optimizing threonine dehydratase or deaminase expression 元素驱动(杭州)生物科技有限公司 2024-09-17 CN claimed
CN-118240726-A Escherichia coli engineering bacteria utilizing sucrose or molasses and method for producing branched chain amino acid by fermentation of escherichia coli engineering bacteria 元素驱动(杭州)生物科技有限公司 2024-06-25 CN claimed
CN-118222648-A Method for producing L-valine and L-isoleucine by using recovered thalli 元素驱动(杭州)生物科技有限公司 2024-06-21 CN claimed
CN-117757704-A Method for improving yield of Branched Chain Amino Acid (BCAA) and strain construction 元素驱动(杭州)生物科技有限公司 2024-03-26 CN claimed
CN-117757651-A Method for improving L-isoleucine yield by optimizing threonine dehydratase or deaminase expression 元素驱动(杭州)生物科技有限公司 2024-03-26 CN claimed
CN-117757860-A Application of threonine extraction waste liquid and/or fermentation liquid in fermentation production of L-isoleucine and fermentation method 元素驱动(杭州)生物科技有限公司 2024-03-26 CN claimed
CN-117757705-A Construction and application of genetic engineering strain capable of realizing co-production of branched-chain amino acid 元素驱动(杭州)生物科技有限公司 2024-03-26 CN claimed
CN-117546851-A Herbicidal compositions containing uracil compounds of carboxylate fragments and uses thereof 江苏中旗科技股份有限公司 2024-02-13 CN claimed
US-20050014647-A1 Method and composition for determining resistance to an acetohydroxy-acid synthase inhibitor BASF AKTIENGESELLSCHAFT (DE) 2005-01-20 US claimed
EP-1417331-A2 IMPROVED METHOD AND COMPOSITION FOR DETERMINING RESISTANCE TO AN ACETOHYDROXYACID SYNTHASE INHIBITOR BASF AKTIENGESELLSCHAFT (DE) 2004-05-12 EP claimed
US-20030180929-A1 Structure-based designed herbicide resistant products AMERICAN HOME PRODUCTS CORPORATION 2003-09-25 US claimed
WO-2003014379-A2 IMPROVED METHOD AND COMPOSITION FOR DETERMINING RESISTANCE TO AN ACETOHYDROXYACID SYNTHASE INHIBITOR BASF AKTIENGESELLSCHAFT (DE) 2003-02-20 WO claimed
EP-0821729-A4 STRUCTURE-BASED DESIGNED HERBICIDE RESISTANT PRODUCTS AMERICAN CYANAMID CO (US) 1999-12-08 EP claimed
US-RE36175-E TREATING SUSCEPTIBLE PLANT WITH COMPOUND AND KETOL-ACID REDUCTOISOMERASE INHIBITOR, TREATING SECOND PLANT WITH INHIBITOR ALONE, MEASURING ACETOLACTATE AND ACETOHYDROXYBUTYRATE FORMED AMERICAN CYANAMID COMPANY (US) 1999-03-30 US claimed
US-5853973-A Structure based designed herbicide resistant products AMERICAN CYANAMID COMPANY (US) 1998-12-29 US claimed
EP-0821729-A1 STRUCTURE-BASED DESIGNED HERBICIDE RESISTANT PRODUCTS AMERICAN CYANAMID COMPANY (US) 1998-02-04 EP claimed
WO-1996033270-A1 STRUCTURE-BASED DESIGNED HERBICIDE RESISTANT PRODUCTS AMERICAN CYANAMID COMPANY (US) 1996-10-24 WO claimed
US-5356789-A For plants; quantitative, colorimetric analysis AMERICAN CYANAMID COMPANY (US) 1994-10-18 US claimed