Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540536 | 0.83 | PKM (0.53) | PKMSOS1HTR6ALDH1A1GAA | |
| SCHEMBL6554230 | 0.82 | MTNR1A (0.44) | PKMPOLBMAPTEPHX2 | |
| SCHEMBL6540377 | 0.81 | ALDH1A1 (0.61) | SOS1ALDH1A1ALOX15GAANPSR1 | |
| SCHEMBL6552306 | 0.78 | HTR6 (0.47) | PKMPOLBMAPTNPC1HTR6 | |
| SCHEMBL1809416 | 0.72 | TAAR1 (0.44) | MAPTSOS1HTR6ALDH1A1KMT2A | |
| SCHEMBL6552312 | 0.72 | HTR6 (0.48) | PKMPOLBMAPTNPC1HTR6 | |
| SCHEMBL6554233 | 0.71 | POLB (0.49) | PKMPOLBMAPTKMT2AMEN1 | |
| SCHEMBL6554319 | 0.70 | HTR2A (0.49) | PKMPOLBMAPTHTR6ALDH1A1 | |
| SCHEMBL6552726 | 0.69 | SLC6A4 (0.46) | PKMPOLBMAPT | |
| SCHEMBL6554126 | 0.69 | POLB (0.46) | PKMPOLBMAPTALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |