⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23499592 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL21134120 | 0.71 | — | — | |
| SCHEMBL22148950 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL6554043 | 0.69 | GPR3 (0.33) | — | |
| SCHEMBL7189284 | 0.68 | GPR3 (0.33) | — | |
| SCHEMBL7085408 | 0.68 | GPR3 (0.33) | — | |
| SCHEMBL20528820 | 0.67 | NPC1 (0.30) | — | |
| SCHEMBL28219801 | 0.66 | AURKA (0.32) | — | |
| SCHEMBL4268439 | 0.64 | MAPK1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL23499500 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11155659-B2 | Dimethyl-silyl-bridged-1-substituted-2-indenyl metallocene complexes for olefin polymerization | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2021-10-26 | — | — | US | disclosed |
| EP-3606967-B1 | DIMETHYL-SILYL-BRIDGED-1-SUBSTITUTED-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2021-08-11 | — | — | EP | disclosed |
| US-20200115478-A1 | DIMETHYL-SILYL-BRIDGED-1-SUBSTITUTED-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-04-16 | — | — | US | disclosed |
| EP-3606967-A1 | DIMETHYL-SILYL-BRIDGED-1-SUBSTITUTED-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION | SABIC Global Technologies B.V. (NL) | 2020-02-12 | — | — | EP | disclosed |
| WO-2018185173-A1 | DIMETHYL-SILYL-BRIDGED-1-SUBSTITUTED-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2018-10-11 | — | — | WO | disclosed |