Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BMP1 | P13497 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5729901 | 0.92 | BCL9 (0.65) | BCL9CTNNB1MAPTRAB9AGAA | |
| SCHEMBL6554410 | 0.90 | BCL9 (0.54) | BCL9CTNNB1MAPTRAB9AGAA | |
| SCHEMBL6554205 | 0.85 | KMT2A (0.57) | BCL9CTNNB1MAPTRAB9AGAA | |
| SCHEMBL16056068 | 0.81 | BCL9 (0.65) | BCL9CTNNB1MAPTRAB9AGAA | |
| SCHEMBL12715327 | 0.80 | BCL9 (0.62) | BCL9CTNNB1MAPTRAB9AGAA | |
| SCHEMBL16055480 | 0.79 | BCL9 (0.61) | BCL9CTNNB1MAPTRAB9AGAA | |
| SCHEMBL16056553 | 0.79 | BCL9 (0.61) | BCL9CTNNB1MAPTRAB9AGAA | |
| SCHEMBL16055727 | 0.79 | BCL9 (0.61) | BCL9CTNNB1MAPTRAB9AGAA | |
| SCHEMBL9523677 | 0.79 | KMT2A (0.60) | BCL9CTNNB1MAPTALDH1A1KMT2A | |
| SCHEMBL6659906 | 0.79 | BCL9 (0.64) | BCL9CTNNB1MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080248584-A1 | Biopolymer ionization; liquid chromatography | OXFORD GENE TECHNOLOGY IP LIMITED (GB) | 2008-10-09 | — | — | US | disclosed |
| US-20080248584-A1 | Biopolymer ionization; liquid chromatography | OXFORD GENE TECHNOLOGY IP LIMITED (GB) | 2008-10-09 | — | — | US | disclosed |
| EP-0898575-B1 | A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES | KOESTER HUBERT DR (US) | 2004-12-29 | — | — | EP | disclosed |
| US-6828435-B2 | Three blocking groups are independently removable under 3 different conditions; using new protection schemes and solid phase synthesis, oligonucleotides are obtained in 5' to 3' direction using phosphoamidites and avoiding depurination | HK PHARMACEUTICALS, INC. | 2004-12-07 | — | — | US | disclosed |
| US-20030194741-A1 | COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES | CAPROTEC BIOANALYTICS GMBH (DE) | 2003-10-16 | — | — | US | disclosed |
| US-20030054410-A1 | Combinatorial protecting group strategy for multifunctional molecules | CAPROTEC BIOANALYTICS GMBH (DE) | 2003-03-20 | — | — | US | disclosed |
| EP-0898575-A2 | A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES | KÖSTER, Hubert (US) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997041139-A2 | A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES | KOESTER HUBERT (US) | 1997-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030194741-A1 | COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES | ADAR, RNMT, ATIC | BCL9 3898/4885CTNNB1 4205/4885MAPT 2388/4885 |
| US-20080248584-A1 | Biopolymer ionization; liquid chromatography | F12, F13B, F13A1 | BCL9 2920/4885CTNNB1 2481/4885MAPT 2903/4885 |
| US-20030054410-A1 | Combinatorial protecting group strategy for multifunctional molecules | ADAR, RNMT, RRM1 | BCL9 4048/4885CTNNB1 4360/4885MAPT 2848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.