SCHEMBL655508

SCHEMBL655508

[c]1nc2ccccc2c2c1ccc1ccccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.39
ALDH1A1 P00352 5/20 0.39
TSHR P16473 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
CYP2A6 P11509 1/20 0.39
HPRT1 P00492 1/20 0.37
HPGD P15428 4/20 0.36
CYP3A4 P08684 2/20 0.36
HIF1A Q16665 2/20 0.36
CASP1 P29466 2/20 0.36
CASP7 P55210 2/20 0.36
MAPK1 P28482 1/20 0.36
RAB9A P51151 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TYMS P04818 2/20 0.36
KDM4E B2RXH2 4/20 0.35
CDK4 P11802 1/20 0.35
CCND1 P24385 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7790782 0.73 ESR1 (0.42) HSD17B10ALDH1A1TDP1HPGDCYP3A4
SCHEMBL24030 0.71 GPR3 (0.46) HSD17B10ALDH1A1TSHRTDP1HPGD
SCHEMBL144610 0.68 HSD17B10 (0.46) HSD17B10ALDH1A1TSHRTDP1CYP2A6
SCHEMBL1869260 0.68 GPR3 (0.54) HSD17B10ALDH1A1TSHRTDP1CYP2A6
SCHEMBL159417 0.67 KDM4E (0.63) HSD17B10ALDH1A1TSHRTDP1CYP2A6
SCHEMBL2514493 0.65 GPR3 (0.34) HSD17B10ALDH1A1HPGDCYP3A4CASP1
SCHEMBL29613365 0.65 HSD17B10 (0.72) HSD17B10ALDH1A1TSHRTDP1CYP2A6
SCHEMBL535472 0.65 HSD17B10 (0.72) HSD17B10ALDH1A1TSHRTDP1CYP2A6
SCHEMBL29388002 0.65 HSD17B10 (0.69) HSD17B10ALDH1A1TSHRTDP1CYP2A6
SCHEMBL30374792 0.65 HSD17B10 (0.69) HSD17B10ALDH1A1TSHRTDP1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220190296-A1 LIGHT-EMITTING DEVICE AND AN ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-06-16 US claimed
EP-1060163-B1 NEW PIPERAZINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES KLINGE CO CHEM PHARM FAB (DE) 2005-10-12 EP claimed
US-6903118-B1 Piperazinyl-substituted pyridylalkane, alkene and alkine carboxamides KLINGE PHARMA GMBH (DE) 2005-06-07 US claimed
US-20240231224-A9 HALOGEN-AND ALIPHATIC-CONTAINING ORGANOTIN PHOTORESISTS AND METHODS THEREOF LAM RESEARCH CORPORATION 2024-07-11 US disclosed
WO-2024137876-A2 SURFACE MODIFICATION OF METAL CATALYSTS WITH HYDROPHOBIC LIGANDS OR IONOMERS TWELVE BENEFIT CORPORATION (US) 2024-06-27 WO disclosed
US-20240200208-A1 CO2 PURIFICATION AND REDUCTION SYSTEMS SUMITOMO MITSUI BANKING CORPORATION 2024-06-20 US disclosed
US-20240192590-A1 APPARATUS AND PROCESS FOR EUV DRY RESIST SENSITIZATION BY GAS PHASE INFUSION OF A SENSITIZER LAM RESEARCH CORPORATION 2024-06-13 US disclosed
WO-2024123514-A1 CO2 PURIFICATION AND REDUCTION SYSTEMS TWELVE BENEFIT CORPORATION (US) 2024-06-13 WO disclosed
CN-118159909-A Gray tone resist and processing 元平台技术有限公司 2024-06-07 CN disclosed
WO-2024108304-A1 DITHIOL CHELATORS FOR METAL CONJUGATION TO ANTIBODIES STANDARD BIOTOOLS CANADA INC. (CA) 2024-05-30 WO disclosed
US-20240134274-A1 HALOGEN-AND ALIPHATIC-CONTAINING ORGANOTIN PHOTORESISTS AND METHODS THEREOF LAM RES CORP (US) 2024-04-25 US disclosed
WO-2005025574-A2 PTERIDINE DERIVATIVES FOR THE TREATMENT OF SEPTIC SHOCK AND TNF-α-RELATED DISEASES. 4 AZA BIOSCIENCE NV (BE) 2005-03-24 WO disclosed
US-20050043541-A1 Metal complexes useful in metathesis and other reactions RIMTEC CORPORATION (JP) 2005-02-24 US disclosed
WO-2004104005-A2 IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES 4 AZA BIOSCIENCE NV (BE) 2004-12-02 WO disclosed
EP-1479682-A1 Immunosuppressive effects of pteridine derivatives 4 AZA Bioscience nv (BE) 2004-11-24 EP disclosed
US-6593344-B1 These substances have especially high cytostatic activities and pronounced immunosuppressive properties which make them suitable for therapeutic treatment in broad tumor spectrum and autoimmune diseases KLINGE PHARMA GMBH (DE) 2003-07-15 US disclosed
EP-1060163-A1 NEW PIPERAZINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES Klinge Pharma GmbH (DE) 2000-12-20 EP disclosed
EP-1044197-A2 NEW PIPERIDINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES Klinge Pharma GmbH (DE) 2000-10-18 EP disclosed
WO-1999031060-A2 PIPERIDINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES AS CYTOSTATICS AND IMMUNESUPPRESSANTS KLINGE PHARMA GMBH (DE) 1999-06-24 WO disclosed
WO-1999031063-A1 NEW PIPERAZINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES KLINGE PHARMA GMBH (DE) 1999-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050043541-A1 Metal complexes useful in metathesis and other reactions TST, ETFA, TTPA HSD17B10 1432/4885ALDH1A1 214/4885TSHR 2092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.