Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.39 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.39 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.38 |
| ▸ | FNTB | P49356 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1922086 | 0.90 | L3MBTL1 (0.56) | L3MBTL1ADORA2AMEN1KMT2ABRCA1 | |
| SCHEMBL4812691 | 0.83 | L3MBTL1 (0.47) | L3MBTL1ADORA2AMEN1KMT2ABRCA1 | |
| SCHEMBL6918767 | 0.80 | L3MBTL1 (0.52) | L3MBTL1ADORA2AMEN1KMT2ABRCA1 | |
| SCHEMBL3153974 | 0.79 | PLA2G1B (0.38) | KMT2AALDH1A1HSD17B10TSHRMAPK1 | |
| SCHEMBL2554376 | 0.75 | L3MBTL1 (0.74) | L3MBTL1ADORA2AMEN1KMT2ABRCA1 | |
| SCHEMBL4382831 | 0.74 | ALDH1A1 (0.37) | L3MBTL1MEN1KMT2ABRCA1ALDH1A1 | |
| SCHEMBL13984089 | 0.74 | L3MBTL1 (0.41) | L3MBTL1ADORA2AMEN1KMT2ABRCA1 | |
| SCHEMBL10508850 | 0.73 | ADORA2A (0.49) | L3MBTL1ADORA2AMEN1KMT2ABRCA1 | |
| SCHEMBL1313857 | 0.72 | ALDH1A1 (0.62) | L3MBTL1ADORA2AMEN1KMT2AALDH1A1 | |
| SCHEMBL1922260 | 0.70 | PLA2G1B (0.43) | L3MBTL1ADORA2AMEN1KMT2ABRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403264-B1 | Process for the industrial synthesis of 5-amino-3-carboxymethyl-4-cyano-2-thiophenecarboxydimethylester | SERVIER LAB (FR) | 2004-12-29 | — | — | EP | claimed |
| WO-2004029035-A1 | NOVEL METHOD FOR THE INDUSTRIAL SYNTHESIS OF THE METHYL DIESTER OF 5-AMINO-3-CARBOXYMETHYL-4-CYANO-2-THIOPHENECARBOXYLIC ACID AND APPLICATION OF DIVALENT SALTS OF RANELIC ACID AND THE HYDRATES THEREOF IN SAID SYNTHESIS | LES LABORATOIRES SERVIER (FR) | 2004-04-08 | — | — | WO | claimed |
| EP-1403264-A1 | Process for the industrial synthesis of 5-amino-3-carboxymethyl-4-cyano-2-thiophenecarboxydimethylester | Les Laboratoires Servier (FR) | 2004-03-31 | — | — | EP | claimed |
| EP-1403264-B1 | Process for the industrial synthesis of 5-amino-3-carboxymethyl-4-cyano-2-thiophenecarboxydimethylester | SERVIER LAB (FR) | 2004-12-29 | — | — | EP | disclosed |
| WO-2004029035-A1 | NOVEL METHOD FOR THE INDUSTRIAL SYNTHESIS OF THE METHYL DIESTER OF 5-AMINO-3-CARBOXYMETHYL-4-CYANO-2-THIOPHENECARBOXYLIC ACID AND APPLICATION OF DIVALENT SALTS OF RANELIC ACID AND THE HYDRATES THEREOF IN SAID SYNTHESIS | LES LABORATOIRES SERVIER (FR) | 2004-04-08 | — | — | WO | disclosed |
| WO-2004029036-A1 | NOVEL METHOD FOR THE INDUSTRIAL SYNTHESIS OF STRONTIUM RANELATE AND THE HYDRATES THEREOF | LES LABORATOIRES SERVIER (FR) | 2004-04-08 | — | — | WO | disclosed |
| EP-1403264-A1 | Process for the industrial synthesis of 5-amino-3-carboxymethyl-4-cyano-2-thiophenecarboxydimethylester | Les Laboratoires Servier (FR) | 2004-03-31 | — | — | EP | disclosed |
| EP-1403266-A1 | Process for the industrial synthesis of strontium ranelate and hydrates thereof | LES LABORATOIRES SERVIER (FR) | 2004-03-31 | — | — | EP | disclosed |