Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.50 |
| ▸ | CCND1 | P24385 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555686 | 0.80 | FGFR1 (0.59) | PPARGHSP90AA1HSP90AB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6557827 | 0.78 | PPARG (0.62) | PPARGALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL6555666 | 0.76 | PPARG (0.76) | PPARGALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL14150946 | 0.70 | WDR5 (0.63) | GPR84ALDH1A1SMN1; SMN2KDM4EHPGD | |
| Acetic Acid SCHEMBL28094251 | 0.69 | MEN1 (0.47) | PPARGGPR84ALDH1A1SMN1; SMN2KDM4E | |
| Ammonia Solution, Strong SCHEMBL23044731 | 0.69 | MAPT (0.53) | CDK4CCND1GPR84ALDH1A1SMN1; SMN2 | |
| SCHEMBL28379153 | 0.69 | HDAC4 (0.57) | CDK4CCND1GPR84ALDH1A1SMN1; SMN2 | |
| SCHEMBL9857384 | 0.68 | ABCG2 (0.50) | CDK4CCND1GPR84ALDH1A1SMN1; SMN2 | |
| SCHEMBL9857357 | 0.68 | ABCG2 (0.50) | CDK4CCND1GPR84SMN1; SMN2KMT2A | |
| SCHEMBL8849960 | 0.67 | PTGS1 (0.48) | KDM4ETDP1L3MBTL1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6146554-A | FOR PHOTOCHROMIC PLASTIC LENSES IN MASS-DYEING PROCESSES | OPTISCHE WERKE G. RODENSTOCK (DE) | 2000-11-14 | — | — | US | disclosed |