Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555666 | 0.89 | PPARG (0.76) | PPARGPTGS1AKR1C3AKR1C2PTPN1 | |
| SCHEMBL6555686 | 0.81 | FGFR1 (0.59) | PPARGPTPN1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8196679 | 0.78 | CDK4 (0.50) | PPARGSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL4658483 | 0.70 | PPARG (0.73) | PPARGPTPN1SMN1; SMN2KDM4EALDH1A1 | |
| Propionic Acid SCHEMBL7100623 | 0.69 | CYP1A2 (0.68) | PPARGPTGS1AKR1C3AKR1C2KDM4E | |
| SCHEMBL6340096 | 0.69 | ME2 (0.73) | SMN1; SMN2KDM4EALDH1A1HPGDGSTP1 | |
| SCHEMBL9890648 | 0.67 | HSD17B10 (0.62) | PPARGPTGS1AKR1C3AKR1C2SMN1; SMN2 | |
| Acetic Acid SCHEMBL7099991 | 0.67 | CYP1A2 (0.76) | PTGS1AKR1C3AKR1C2SMN1; SMN2KDM4E | |
| SCHEMBL25041887 | 0.67 | CYP1A2 (0.83) | CYP11B1CYP11B2SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3572575 | 0.67 | PPARG (1.00) | PPARGSMN1; SMN2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958288-B1 | PHOTOCHROMIC NAPHTOPYRANE COLORANTS, METHOD FOR THE PRODUCTION AND USE THEREOF, PHOTOCHROMIC OBJECT | RODENSTOCK GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6146554-A | FOR PHOTOCHROMIC PLASTIC LENSES IN MASS-DYEING PROCESSES | OPTISCHE WERKE G. RODENSTOCK (DE) | 2000-11-14 | — | — | US | disclosed |
| EP-0958288-A1 | PHOTOCHROMIC NAPHTOPYRANE COLORANTS, METHOD FOR THE PRODUCTION AND USE THEREOF, PHOTOCHROMIC OBJECT | Optische Werke G. Rodenstock (DE) | 1999-11-24 | — | — | EP | disclosed |
| WO-1999015518-A1 | PHOTOCHROMIC NAPHTOPYRANE COLORANTS, METHOD FOR THE PRODUCTION AND USE THEREOF, PHOTOCHROMIC OBJECT | OPTISCHE WERKE G. RODENSTOCK (DE) | 1999-04-01 | — | — | WO | disclosed |