Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811056 | 0.93 | PGR (0.49) | PARP1ACHEPARP10HTR2AHTR2C | |
| SCHEMBL6557452 | 0.89 | ALDH1A1 (0.53) | PARP1ACHEHTR2AHTR2CPGR | |
| SCHEMBL577480 | 0.83 | PGR (0.49) | PARP1ACHEPARP10PGRCA1 | |
| SCHEMBL24727259 | 0.83 | METAP1 (0.44) | PARP1ACHEPARP10HTR2AHTR2C | |
| SCHEMBL9810960 | 0.83 | LMNA (0.63) | PARP1ACHEPARP10HTR2AHTR2C | |
| SCHEMBL21801625 | 0.80 | PARP1 (0.40) | PARP1ACHEPARP10HTR2AHTR2C | |
| SCHEMBL5080927 | 0.79 | ALDH1A1 (0.59) | PARP1ACHEHTR2AHTR2CPGR | |
| SCHEMBL20651117 | 0.79 | ACHE (0.43) | PARP1ACHEPARP10HTR2AHTR2C | |
| SCHEMBL29851576 | 0.79 | ALDH1A1 (0.59) | PARP1ACHEHTR2AHTR2CPGR | |
| SCHEMBL17068947 | 0.79 | ALDH1A1 (0.59) | PARP1ACHEHTR2AHTR2CPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655264-B2 | Metallocene compounds, and preparation and use thereof for synthesis of poly-alpha-olefins as lubricating base oil | APALENE TECHNOLOGY CO., LTD. (HANGZHOU) (CN) | 2023-05-23 | — | — | US | disclosed |
| CN-105384611-B | A kind of electron donor of Ziegler-Natta catalyst and preparation method thereof | 亚培烯科技（杭州）有限公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-108559012-A | Synthetic lubricant base oil metallocene poly-alpha olefins catalyst and its preparation and application | 亚培烯科技（杭州）有限公司 | 2018-09-21 | — | — | CN | disclosed |
| US-20180258112-A1 | Metallocene compounds, and preparation and use thereof for synthesis of poly-alpha-olefins as lubricating base oil | APALENE TECHNOLOGY CO., LTD. (JIAXING) (CN) | 2018-09-13 | — | — | US | disclosed |
| CN-106146692-A | Synthetic lubricant base oil metallocene poly-alpha olefins catalyst and its preparation method and application | 苏州亚培克生物科技有限公司 | 2016-11-23 | — | — | CN | disclosed |
| CN-106046211-A | Metallocene poly-alpha olefin catalyst for synthesizing lubricating oil base oil and preparation method and application thereof | 苏州亚培克生物科技有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-105669902-A | Novel cycloolefin copolymer catalyst and synthetic method thereof | 魏东初 | 2016-06-15 | — | — | CN | disclosed |
| CN-105384611-A | Electron donor of Ziegler-Natta catalyst and preparation method of electron donor | SUZHOU APAC BIOLOGICAL SCIENCE & TECH CO LTD | 2016-03-09 | — | — | CN | disclosed |
| CN-105348330-A | 3 mono-substituted or 3,6 bis-substituted fluorenyl metalloscene and preparation method and application thereof | SUZHOU APAC BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2016-02-24 | — | — | CN | disclosed |
| CN-105330508-A | 3-monosubstituted or 3,6-disubstituted fluorene derivative and preparing method and application thereof | SUZHOU APAC BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2016-02-17 | — | — | CN | disclosed |
| US-8084559-B2 | Ethylene-vinylcyclohexane copolymers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-27 | — | — | US | disclosed |
| US-20080161514-A1 | Transition Metal Complex, Process For Producing Said Transition Metal Complex, Substituent-Carrying Fluorene Compound, Process For Producing Said Fluorene Compound, Catalyst Component For Olefin Polymerization, Catalyst For Olefin Polymerization, and Process For Producing Olefin Polymer | SUMITOMO CHEMICAL COMPANY, LIMTIED (JP) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161514-A1 | Transition Metal Complex, Process For Producing Said Transition Metal Complex, Substituent-Carrying Fluorene Compound, Process For Producing Said Fluorene Compound, Catalyst Component For Olefin Polymerization, Catalyst For Olefin Polymerization, and Process For Producing Olefin Polymer | AOC2, ACSL1, ACSL3 | PARP1 1060/4885ACHE 3763/4885PARP10 318/4885 |
| US-11655264-B2 | Metallocene compounds, and preparation and use thereof for synthesis of poly-alpha-olefins as lubricating base oil | POLM, POLA1, POLD1 | PARP1 38/4885ACHE 1963/4885PARP10 427/4885 |
| US-20180258112-A1 | Metallocene compounds, and preparation and use thereof for synthesis of poly-alpha-olefins as lubricating base oil | POLM, POLA1, POLD1 | PARP1 38/4885ACHE 1963/4885PARP10 427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.