Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29383126 | 1.00 | AGTR1 (0.36) | AGTR1AGTR2TBXA2RPDE3A | |
| SCHEMBL9533005 | 0.80 | POLB (0.47) | AGTR1AGTR2 | |
| SCHEMBL8543595 | 0.79 | CASP3 (0.46) | — | |
| SCHEMBL9532996 | 0.79 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL14464087 | 0.78 | AGTR1 (0.43) | AGTR1AGTR2PDE3A | |
| SCHEMBL448437 | 0.76 | POLB (0.55) | AGTR1AGTR2TBXA2RPDE3A | |
| SCHEMBL6962635 | 0.76 | AKT1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL9533000 | 0.74 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL588365 | 0.74 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL8700752 | 0.74 | AGTR1 (0.49) | AGTR1AGTR2PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1393722-A2 | Use of angiotensin II subtype 1 (AT1) antagonists for the manufacture of a medicament in the treatment of premenstrual syndrome | DePadova, Anthony S. (US) | 2004-03-03 | — | — | EP | claimed |