Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533005 | 0.82 | POLB (0.47) | AGTR1AGTR2GRM2 | |
| SCHEMBL8543595 | 0.79 | CASP3 (0.46) | — | |
| SCHEMBL29383126 | 0.79 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL6556670 | 0.79 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL6962635 | 0.76 | AKT1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL3376281 | 0.76 | TRPA1 (0.35) | AGTR1AGTR2 | |
| SCHEMBL29366164 | 0.76 | TRPA1 (0.35) | AGTR1AGTR2 | |
| SCHEMBL8702000 | 0.75 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9533000 | 0.74 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL588365 | 0.74 | AGTR1 (0.41) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555331-A1 | N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS. | SEARLE & CO (US) | 1993-08-18 | — | — | EP | disclosed |