SCHEMBL6557066

SCHEMBL6557066

Cn1nc(CCOC(c2ccccc2)(c2ccccc2)c2ccccc2)c(NC=O)c1N

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.38
TERT O14746 1/20 0.34
TK2 O00142 10/20 0.34
SLC6A1 P30531 3/20 0.33
TK1 P04183 1/20 0.33
HRH4 Q9H3N8 1/20 0.32
SLC6A11 P48066 1/20 0.31
DUT P33316 1/20 0.31
TYMP P19971 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5147569 0.78 KIF11 (0.38) KIF11TK2SLC6A1TK1
SCHEMBL5009896 0.67 LTB4R (0.32) TERT
SCHEMBL6557071 0.66 KIF11 (0.38) KIF11HRH4DUT
SCHEMBL5147565 0.64 KIF11 (0.40) KIF11TK2SLC6A1TK1HRH4
SCHEMBL7305154 0.63 PKM (0.43)
SCHEMBL5147531 0.63 KIF11 (0.42) KIF11TK2SLC6A1TK1HRH4
SCHEMBL11275984 0.60 KIF11 (0.74) KIF11TK2SLC6A1TK1HRH4
SCHEMBL6558785 0.60 KIF11 (0.42) KIF11TK2HRH4DUT
SCHEMBL9039609 0.60 KIF11 (0.57) KIF11TK2SLC6A1TK1HRH4
SCHEMBL19393417 0.60 KIF11 (0.52) KIF11TK2SLC6A1TK1HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1392704-A1 CEPHEM COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-03 EP disclosed
WO-2002090364-A1 CEPHEM COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-11-14 WO disclosed