Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.37 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27509354 | 0.81 | ACHE (0.39) | CA1CA2CA4CA6PNMT | |
| SCHEMBL27493543 | 0.81 | PGR (0.39) | CA1CA2CA4CA6PNMT | |
| SCHEMBL6558006 | 0.78 | PGR (0.42) | PARP1CA1CA2CA4CA6 | |
| SCHEMBL4359047 | 0.78 | PNMT (0.53) | CA1CA2CA4CA6PNMT | |
| SCHEMBL6555945 | 0.77 | PNMT (0.41) | CA1CA2CA4CA6PNMT | |
| SCHEMBL6557452 | 0.74 | ALDH1A1 (0.53) | PARP1CA1CA2CA4CA6 | |
| SCHEMBL7111301 | 0.73 | PNMT (0.41) | CA1CA2CA4CA6PNMT | |
| SCHEMBL28568070 | 0.72 | PNMT (0.52) | CA1CA2CA4CA6PNMT | |
| SCHEMBL9811068 | 0.71 | PNMT (0.46) | CA1CA2CA4CA6PNMT | |
| SCHEMBL5080927 | 0.69 | ALDH1A1 (0.59) | PARP1CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223209-B1 | Fluorinated fluorenes and use thereof in liquid crystal mixtures | CLARIANT INT LTD (CH) | 2004-03-03 | — | — | EP | disclosed |
| EP-1223209-A1 | Fluorinated fluorenes and use thereof in liquid crystal mixtures | CLARIANT INTERNATIONAL LTD. (CH) | 2002-07-17 | — | — | EP | disclosed |