SCHEMBL6558335

SCHEMBL6558335

[CH](O[CH]c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
MAOB P27338 2/20 0.45
TSHR P16473 1/20 0.45
CYP2A6 P11509 1/20 0.45
LMNA P02545 3/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
TRPA1 O75762 2/20 0.39
NFE2L2 Q16236 1/20 0.38
CYP19A1 P11511 1/20 0.38
MAOA P21397 1/20 0.38
ALOX5 P09917 1/20 0.38
MAPK1 P28482 1/20 0.38
IDO1 P14902 2/20 0.37
ESR1 P03372 1/20 0.37
HDAC3 O15379 1/20 0.36
TNKS O95271 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL434609 0.83 ALDH1A1 (0.50) ALDH1A1MAOBTSHRCYP2A6LMNA
SCHEMBL6932980 0.83 ALDH1A1 (0.38) ALDH1A1MAOBTSHRCYP2A6LMNA
SCHEMBL9444804 0.83 ALDH1A1 (0.50) ALDH1A1MAOBTSHRCYP2A6LMNA
SCHEMBL9491570 0.81 MAOB (0.48) ALDH1A1MAOBLMNATRPA1NFE2L2
SCHEMBL4354058 0.75
SCHEMBL8 0.75
SCHEMBL6258234 0.75
SCHEMBL18640421 0.75
SCHEMBL3855904 0.75
SCHEMBL9798232 0.73 ALDH1A1 (0.39) ALDH1A1MAOBTSHRCYP2A6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3946064-A EXPANDING POLYMERS UNIROYAL, INC. (US) 1976-03-23 US claimed
US-6696595-B2 ESTERIFYING AN ADAMANTANE COMPOUND HAVING AN -OH GROUP, -OM GROUP OR OR DIVALENT ALIPHATIC HYDROCARBON GROUP, AND DISTILLING THE ESTER PRODUCT IN PRESENCE OF AN INERT HETEROCYCLIC COMPOUND WHICH IS STABLE UNDER DISTILLATION TOKUYAMA CORPORATION (JP) 2004-02-24 US disclosed
US-20030120107-A1 Process of the preparation of high-purity alkyladamantyl esters TOKUYAMA CORPORATION (JP) 2003-06-26 US disclosed
EP-1284256-A1 PROCESS OF THE PREPARATION OF HIGH-PURITY ALKYLADAMANTYL ESTERS TOKUYAMA CORPORATION (JP) 2003-02-19 EP disclosed
US-4245060-A TOUGH, DURABLE COATINGS EXXON RESEARCH & ENGINEERING CO. (US) 1981-01-13 US disclosed
US-3946064-A EXPANDING POLYMERS UNIROYAL, INC. (US) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030120107-A1 Process of the preparation of high-purity alkyladamantyl esters TET2, MSMO1, ACMSD ALDH1A1 591/4885MAOB 2462/4885TSHR 4023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.